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Home My WebLink About1890 RUTHERFORD RD; ; CB121347; PermitCity of Carlsbad 12-12-2012 1635 Faraday Av Carlsbad, CA 92008 Commercial/Industrial Permit Permit No: CB121347 Building Inspection Request Line (760) 602-2725 Job Address: 1890 RUTHERFORD RD CBAD Permit Type: Tl Sub Type: INOUST Status: ISSUEO Applied: 07/17/2012 Entered By: JMA Parcel No: 2121203500 Lot#: 0 Valuation: $18,931.00 Construction Type: NEW Occupancy Group: Reference# Plan Approved: 12/12/2012 Issued: 12/12/2012 Inspect Area Project Title: GENOPTIX: 510 SF Tl OF EXISTIN LAB Applicant: DAVID BOYD FERGUSON PAPE ARCH. 4499 RUFFIN RD., #300 SAN DIEGO CA 92123 619-231-0751 Building Permit Add'I Building Permit Fee Plan Check · Add'I Building Permit Fee Plan Check Discount Strong Motion Fee Park Fee LFM Fee Bridge Fee STD #2 Fee BTD#3 Fee Renewal Fee Add'I Renewal Fee Other Building Fee Pot. Water Con. Fee Meter Size Add'I Pot. Water Con. Fee Reel. Water Con. Fee · Green Bldg Stands (SB1473) Fee Fire Expedidted Plan Review $215.07 $0.00 $150.55 $0.00 $0.00 $3.98 $0.00 '$0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $1.00 $0.00 '-. Total Fees: $518.60 Total Payments To Date: Plan Check #: Owner: RE:DUS CARLSBAD L L C 3563 PHILLIPS HWY #601 E JACKSONVILLE FL 32207 Meter Size Add'I Reel. Water Con. Fee Meter Fee SDCWA Fee CFO Payoff Fee PFF (3105540) PF'F (4305540) l.,.icense Tax (3104193) Licens·e Tax (4304193) Traffic Impact Fee (3105541) Traffic Impact Fee (4305541) PLUMBING TOTAL ELECTRICAL TOTAL MECHANICAL TOTAL Master Drainage Fee ,Sewer Fee Re<;lev Parking Fee Additional Fees HMP.fee Green Bldg Standards Plan Chk TOTAL PERMIT FEES $518.60 Balance Due: $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $58.00 $51.00 $39.00 $0.00 $0.00 $0.00 $0.00 ?? ?? $518.60 $0.00 Inspector: FINAL mrJVAL Date: l> J,,6/3 . ~ .'-Clearance: ------ NOTICE: Please take N TICE t approval of your project includes the 'Imposition' of fees, dedications, reservations, or other exactions hereafter collectively referred to as "fees/exactions." You have 90 days from the date this permit was issued to protest imposition of these fees/exactions. If you protest them, you must follow the protest procedures set forth in Government Code Section 66020(a), and file the protest and any other required information with the City Manager for processing in accordance with Carlsbad Municipal Code Section 3.32.030. F.:iilure to timely follow that procedure will bar any subsequent legal action to attack, review, set aside, void, or annul their imposition. You are hereby FURTHER NOTIFIED that your right to protest the specified fees/exactions DOES NOT APPLY to water and sewer connection fees and capacity changes, nor planning, zoning, grading or other similar application processing or service fees in connection with this project. NOR DOES IT APPLY to any fees/exa lions f wtii h h v r vi I n iv n N Tl imil r· his · r whi h he t ute f limit i ns ha revi usl otherwise ex ired. \ _\,. ·--· (' • Building Permit Application Plan Check No.CB (2. .. l'3lt7 Est. Value qlf'J'131· 1635 Faraday Ave., Carlsbad, CA 92008 W CITY OF 760-602-2717 / 2718 / 2719 Plan Ck. f?eposlt CARLSBAD Fax 760-602-8558 www.carlsbadca.gov Date '1 /17 /1 z lswPPP JOB ADORES$, 1890 Rutherford Rdk Carlsbad, CA 92008 SUITEf/SPACEf/UNIT# IAPN 212 200 -120 -29 - CJ/PROJECT# rOT# rHASw~ ro;;;s r BED~;; #BATHROOMS I TENANT BUSINESS NAME rONSTR. lYPE I ace, GROUP 47 N/A Genoptix Inc. 111-B B,A3,at DESCRIPTION OF WORK: Include Square Feet of All'ected Area(s) AREA OF WORK IS~-ARCHITECTURAL: 1. DEMO OF EXISTING LABS, CEILINGS, FLOORING. 2. REBUILD OF LABS, NEW FLOORING/ CEILING. MECHANICAL: 1. NEW HVAC FOR NEW LABS 2. CONVERSION OFHVAC TO SINGLE PASS AIR IN SEU;CT AREAS OUTSIDE OF LAB T.I. EXISTING USE ., PROPOSED USE I GARAGE (SF) PATIOS (SF) I DECKS (SF) FIREPLACE rR CONDITIONING I FIRE SPRINKLERS OFFICEJLAB NO°CHANGE · NIA N/A N/A YESQ, No{ZJ vEs (ZINo D · YEs(ZI NoD APPLICANT NAME (Primary Contact) Ferguson Pape Baldwin Archltecu APPLICANT NAME (Secondary Contact} MykeSmith ADDRESS ADDRESS 4499 R~ffln Rd~ S~e. 300 2110 Rutherford Rd. CITY STATE ZIP CITY STATE ZIP San Dle"o CA 92123 Carlsbad CA 92008 PHONE rAX PHONE 760-268-6200. IFAX 619~231-0751 EMAIL EMAIL dboyd@fpbarch.com msmith@genoptix.com PROPERTY OWNER NAME Diversified PrQpertie.s CONTRACTOR BUS. NAME Good and Roberts ADDRESS ADDRESS 1.825 GIiiespie Wav, Suit, 102 1330 Park Center Drive CITY STATE ZIP CITY . STATE ZIP El Calon CA 92020 Vista CA 92081 PHONE IFAX PHONE IFAX 619.258.2900 619.258.2909. 760.598.7614 EMAIL EMAIL ARCH/DESIGNER NAME & ADDRESS 15TATE LIC. # ~ATE UC,# 'I ICLA$ i<ITYBitq 53-S-3 0 i ~77~S-, have an~ wHI 11111lntaln a certlflcate of consent to 111f-lnsu11 for WO!kers' compensation as provided by Section 3700 of.lite labor Code, for the performance of lhe work for which this pennll ls Issued. .,, ers' Compensation Dtcl1ratlon: / hereby affirm under pena/tyof p«jlxyone of the fdlowing declarations: I have and wHI 11111lntaln w~rs' compensation, as leQUked by Section 3700 of the labor Code, for the performance of the WOik for which !his ~it is issued. My workers' compensalion~uranz earlier and policy :numberare:lnsuranceeo.55:..oen::Y Uft'f"IC;»,)*1.-I~ G;».0.,,..,\7 PolicyNo. 'SWC. lO\ '36e>t, ExpiralionDate {C>LOI_ I~ . . . ]]:1§,secllon need not be compeled if the pennit is for one hundied doll!S ($100) or less. LJ ,Ct!llllcate of Exempllon: I certify lhat in the pelfonnance or the WOik for Ytfllch this pem11t Is Issued, I shall not employ ooy person In any manner so as to become subject to the WO!kers' Compensatton Laws of C IWomla. WARNING: F1llu11 to 11cu11 workn' coverage i unlawful, and sli1H subjectln employer to crlmlnal penalUes and civil fines up to one hundred thousand dollars (&100,000), in · ddlUon to the costofccmpen dtd for In S 37 ·, eiutanil attorney's fees. ! N$ CONTRACTORSIGNATU 1111111! DATE ' /2 I z_ I I hereby affirm that I am exempt from Coolnlctor's Law follcwrlng ieason: 0, I, as owner of the property or my employees with as ll1eir sole compensation, wil !lo 1he WOik and the slruclure is not lo tended or offered for sale (Sec. 7044, Business and Professions Code: The Contracto(s . License Law does not 8llPIY lo an owner or property who blilds or Improves thereon, and who does such work himseW or through his own employees, provided !hat such Improvements are not iotended or offered for sale. If, however, the building or lmpro\'91ll81ll Is sold wllhln one year or completion, the owner-builder Win have the burden of proving that he did not buil:I or Improve for the IJIKl)Ose or sale). D I, as owner of the property, am excklslveiy conflacllng wl1h llcensed connctors to constnx:t lhe project (Sec. 7044, Business and Professioos Code: The Conlractol's Ucense Law does not apply to an owner of property who buiklsorlmproves thefeqn, and conncts for such projects with contractor(s) ilcensed JlUISUMI to the Contractor's License Law}. D I am exempt under Section ~~--·Business arxl Professions Code for !his reason: 1. I pe1SOnally plan to proylde the major labor and malerlals for construction or the proposed property Improvement. Oves Oo 2.1 (have/ have not) signed an appllcatlon for a bulcllng permit for the proposed .work. 3.1 have conlracted with the foilowlng person (flnn) lo provide the proposed construction [mclude name irllress /phone/ contractors' license number): 4.1 plan to provide portions of the WOik, but I have hied the loHowlng person lo coordinate, supervise and provide the major work Qnciude name/ address I phone / contractors' license number): 5.1 wlll provide some of the work, but I have ~acted (hiad) the following persons to provide the work indicated Qncilide name/ address/ phone/ type of work): NS PROPERTY OWNER SIGNATURE 0AGENT DATE ,4 •• • • • .. Is the applicant or future buildlng occupant required lo submij a buslne5Y!I!, acuely hazardous materials registration form or risk management and prevenllon program under Secllons 25505, 25533 or 25534 of the Presley-Tanner H!!Zardous Slibslance Account Act? [2J Yes LJNo Is the applicant orfutum buildlng occupant required to obtain a permit from the air ~llon contro!Jllilricl oralr_swality management dlstrlcl? @ves D No Is the faciilylo lleconstrucledwilhln 1,000feet of the outer boundaiy of aschool site? LJYes L!.JNo IF ANY OF THE ANSWERS ARE YES, A ANAL CERTIFICATE OF OCCUPANCY MAY NOT BE ISSUED UNLESS THE APPLICANT HAS MET OR IS MEETING THE REQUIREMENTS OF THE OFFICE OF EMERGENCY SERVICES AND THE AIR POLLUTION CONTROL DISTRICT. . I hereby affirm l!lat there is a construction lending !19ency for the performance of the work this permit is issued (Sec. 3097 (i) Civil Code). Lender N ,-------·-~----.._.._ ______ ,_. ____ }L der' Addrj ~ --~-~ .. -----------....... ~ ---~--.,,.. -1...., __ _ s ame; = __ . _ ~ .. __ : _ ~---------·-·. ~ .·--· .... __ . ___ , en s ess . .,_: ...... ,-, '.;;. .. _j I certify that I have readtheapplk:atfonanci sllltethatthe above lnformallon lsconectandthatthe lnformallon on the plansls accurate. I .iweeto comply I'll th all Cityortllnancesand State laws relallngtobulklng construction. I he/ebyaulhorize replllS8flfaliwof the Cityof Cafsbal to enleruP911 lhe aboYe mentioned ~b'inspection puposes. I ALSO AGREE TO SAVE, INDEMNIFY AND KEEP HARMLESS THE CITY OF CARLSBAD AGAINST All LIABILITIES, JUDGMENTS, COSTS AND EXPENSESWHIOI MAY IN AtNWAY ACCRUE AGAINST SAl.0 CITY IN CONSEQUENCE OF THE GRANTING OF THIS PERMIT. OSHA: An OSHA permit is requied b' excavations oYlir 5'11 deep and demoli:>n oroonslruction or structures over 3 stories n height. EXPIRATION: Every pennit Issued by the Biting Olkial ooderthe proa,;sions of this Codeshal expire by irnilaion and become null and YOiil if the buildi(ll or'Mllk authorized by such permit Is not commenced within 180d~ from theQateof such permit or if the bulldilg or'Mllkaulhorized by such permit ls suspended or abandoned at anytime after the 'Mllkls corrmenced fora period of 180days (Section 106.4.4 Uniform Buikling Code) . ..@S'.a.ePLICANT'SSIGNATURE ~~ ~ DATE _ tf, 'Z,l:J>/ Z. (_, 1-nspection List Permit#: CB121347 Type: Tl Date Inspection Item · 04/09/2013 89 Final Combo 04/09/2013 89 Final Combo 04/05/2013 89 Final Combo 04/05/2013 89 Final Combo 03/19/2013 17 Interior Lath/Drywall 03/18/2013 17 Interior Lath/Drywall 03/14/2013 14 Frame/Steel/Bolting/Weldin 03/14/2013 24 Roughffopout 03/14/2013 34 Rough Electric 03/07/2013 21 Underground/Under Floor 03/07/2013 24 Rough/Topout 03/0712013 34 Rough Electric Wednesday, April.10, 2013 INDUST Inspector Act RI PY AP RI MC CA PY AP PY AP PY AP PY AP PY AP PY AP PY AP PY AP GENOPTIX: 510 SF Tl OF EXISTIN LAB C9mrnents AM PLS AM-COF PER CONTRACTOR Page 1 of 1 . POOR QUALITY ORIGINAL. S 5 I DATE: 7/25/12 EsGil Corporation In <Partnersliip witfi qovernment for (}Jui{aing Safety JURISDICTION: City of Carlsbad PLAN CHECK NO.: 12-1347 SET:I PROJECT ADDRESS: 1890 Rutherford Rd Suite 200 PROJECT NAME: Genopti.x AFQ Lab -TI CJ APPLICANT lafJURIS. CJ PLAN REVIEWER CJ FILE ~ The plans transmitted herewith have been corrected where necessary and substantially comply with the jurisdiction's codeit. D The plans transmitted herewith will substantially comply with the jurisdiction's codes when minor deficiencies identified below are resolved and checked by building department staff. D The plans transmitted herewith have significant deficiencies identified on the enclosed check list and should be corrected and resubmitted for a complete recheck. D The check list transmitted herewith is for your information. The plans are being held at Esgil Corporation until corrected plans are submitted for recheck. D The applicant's copy of the check list -is enclosed for the Jurisdiction to forward to the applicant contact person. D T_he applicant's copy of the check Hst has been $ent to: ~ EsGil Corporation staff did not advise the applicant that the plan check has been completed. D EsGil· Corporation staff did advise th~ applicant that the plan check has been completed. Person contacted: Date contacted: (by: Telephone#: ) Email: Maii Telephone Fax In Person D REMARKS: By: Doug Moody EsGil Corporation D GA D EJ D PC .,._ Enclosures: 7/19/t2 Fax#: 9320 Chesapeake Drive, Suite 208 + San Diego, California 92123 + (858) 560-1468 + Fax (858) 560-1576 ' ;,. City of Carlsbad 12-1347 7/25/12 [DO NOT PAY -THIS IS NOT AN INVOICE] VALUATION AND PLAN CHECK FEE JURISDICTION: City of Carlsbad PREPARED BY: Doug Moody PLAN CHECK NO.: 12-1347 DATE: 7/25/12 BUILDING ADDRESS: 1890 Rutherford Rd Suite 200 BUILDING OCCUPANCY: B TYPE OF CONSTRUCTION: IIIB BUILDING AREA Valuation Reg. VALUE PORTION ( Sq. Ft.) Multiplier Mod. Tl 510 . 37 .. 12 Air Conditioning Fire Sprinklers TOTAL VALUE Jurisdiction Code cb By Ordinance Bldg. Permit Fee by Ordnance ... Plan OleckFeeby0rdinance "" Type of Review: El Complete Review D Structural Only ORepetitive Fee ,.. Repeats Comments: D Other D Hourly EsGil Fee 1---------11 Hr. @ • ($) 18 931 18,931 $215.07! $139.aol $120.441 Sheet 1 of 1 macvalue.doc + ,, ~ «.,~ ~ CITY OF CARLSBAD PLAN CHECK REVIEW TRANSMITTAL Community & Economic Development Department 1635 Faraday Avenue Carlsbad CA 92008 www.carlsbadca.gov DATE: 8/07/12 PROJECT NAME: Genoptix .Medical Lab(CRC Lot 47) PLAN CHECK NO:CB 12-1347 SET#: I ADDRESS: 1890 Rutherford Rd VALUATION: $18,931 PROJECT ID:CT 85'.'24 APN: 212-120-35 · · This plan check review is eomplete and has been APPROVED by: [l] . . . By: LAND .DEVELOPMENT ENGINEERING DIVISION A Final Inspection by the Construction Mgmt a: Inspection Division is required Oves ~ No This plan check review is NOT COMPLETE. Items missing or incorrect are listed on o the attached checklist. Please resul:miit amended plans as required. Plan Check Comments have been sent to: You may also have corrections from one or more of the divisions listed below. Approval from these divisions may be required prior to the issuance of a building permit. Resubmitted plans should _include corrections from .all divisions . ·PLANNING 760-602-4610 . ; I ENGiN~E,RING·~:-' ~ ."·':FIRE':PR'EVENTION' '• '" I · 1a0-:Go2~21so . · ·· : · · 1 · · 1t6o~ao~-46Ss . . .. · · · •-• l f ...:--..-:--.:....-..... .., ....... ,'t""M.... ...,,_, ,,...,,..,_ .,....:,...,._ <; ""' ·-~ " J, .•• <, < ; " • ':~, ::', ,> I .. I Chris.Sexton I; 1·_]-Kathleen Lawrence · 17 ! Greg Ryan I\ 760-602-4624 I.· 760-602-2741 ii · 760-602-4663 Chris.Sexton@carlsbadca.gov [.: Kathleen.Lawrence@carlsbadca.gov Gregory.Ryan@carlsbadca.gov 11-------~----,.-----------,------,:ii------------' i; IXI Li_nda Ontiveros 17 Cindy Wong 1 1,. 160-602-2113 1-· 160-602-4662 , . Linda.0ntiveros_(!jlcarlsbad.ca.gov Cynthia.Wong@carlsbadca.gov r 1· Gina Ruiz ' . 760-602-4675 Gina.Ruiz@carlsbadca.gov f---i---,-----------'--,----..,j·u_-lr---_-1 _D_o_m-in_i_c_F-ie-ri------1:11 J : l--1 ·-1 760-602-4664 _ ii~ Dominic.Fieri@c~lsbadca.gov · For-questions or clarifications on th~ attached checklist please contact the reviewer as marked above. Remarks: «~ ~ C_ITY OF CARLSBAD BUILDING PLANCHECK CHECKLIST QUICK-CHECK/APPROVAL Development Services Land Development Engineering 1635 Faraday Avenue 760-602-2750 www.carlsbadca.gov ENGINEERING Plan Check for CB 12-1347 Date: 8/07 /12 P : t Add 1890 Rutherford Rd roJec ress: APN: 212-120-35 Project Description: ~ 10 sf tenant improvement of existing lab Valuation: $18,931 space -no change in use. · ENGINEERING Contact: Linda Ontiveros Phone: 760-602-2773 0 RESIDENTIAL . 0 RESIDENTIAL ADDITION MINOR (<$20,000.00) 0 CARLSBAD PREMIER OUTLETS O0THER: Email: linda.ontiveros@carlsbadca.gov Fax: 760-602-1052 IZ]TENANT IMPROVEMENT . 0 PLAZA CAMINO REAL 0 COMPLETE OFFICE BUILDING r ........ ~. ~ ... --····-.. --·. -... -.. -OF°FtciAtuse·'o1i'LY . ._ .... ~ .. ~ .. ~-·:-.. _,,. -.. , ,. ENGINEERING AUTHORIZATION. T,O 1$.SIJI; BUILDING PERMIT · 1 I· ' . I ,, . . I r - . :-. ; · ·oAti::8/07/12 . . . -I ',• I!' r -· I -• •. _...-. • -.,.,_ • •--• ~ -••.-a. -I I -I I -I I -I ....... 1•1 -~-I _,1 I -I., ..... I I -I I -I I -Ii Page 1 of 1 REV 4/30/11 «~~ ~ CITY OF CARLSBAD DATE: 7/17/'12 PROJECT NAME: PLAN CHECK REVIEW TRANSMITTAL PROJECT ID: Community & Economic Development Department 1635 Faraday Avenue Carlsbad CA 92008 www.carlsbadca.gov PLAN CHECK NO: CB12134 7 SET#: ADDRESS: 1890 RUTHERFORD RD APN: 212-120-35-00 ~ This plan check review is ·complete and has been APPROVED by the PLANNING Division. By: GINA RUIZ A .Final Inspection by the PLANNING Division is requi·red D Yes [8] No D This plan check review is NOT COMPLETE .. Items missing or incorrect are listed on the attached checklist. Please resubmit amended plans as required. Plan Check APPROVAL has been sent to: DBOYD@FPBARCH.COM You may also have corrections from one or more of the divisions listed below. Approval from these divisions may be required prior fo the issuance of a building permit. Resubmitted .plans should include corrections from all divisions. For qu~~tions or clarifications on the attached checklist please .contact the following reviewer as marked: .. ; -. '·' -. ,, ·:··;-- PLANNING, ENGIN·EERIN'G ·, . .. Fd~E''PREVENTft>N·, ! ,, ,· ; , ,· < '. : • 760-602-4610 760-602-2750 · ,, 760~602~4665 ·.: '., ·, '(.' ,. '', -. . -.. - D Chris Sexton D Kathleen Lawrence D Greg Ryan 760-602-4624 760-602-27 41 760-602-4663 Chris:Sexton@carlsbadca.gov Kathleen.Lawrence@carlsbadca.gov Grego!}'..R~an@carlsbadca.gov .. D Gina Ruiz D Linda Ontiveros ·D Cindy Wong 760-6024675 760-602-2773 760-602-4662 Gina.Ruiz@carlsb~dca.gov Linda.Ontiver.os@carlsbadca.gov Cynthia.Wong@carlsbadca.gov D D D Dominic Fieri 760-602-4664 Dominic.Fieri@carlsbadca.gov Remarks: '~ .. «.! ... ~ · -~ CITY OF CARLSBAD PLAN CHECK REVIEW TRANSMITTAL !iUILDING [H:PT,, Co~,;;t.~;; & Economic Development Department 1635 Faraday Avenue Carlsbad CA 92008 www.carlsbadca.gov DATE: 07/23/2012 PROJECT NAME: GENOPTIX -AFQ LABS PROJECT ID: CB121347 PLAN CHECK NO: 1 SET#: 1 APDRESS: 1890 RUTHERFO.RD RD APN: 212-120-29 gJ This plan check review is complete a·nd has been APPROVED by the FIRE Division. By: GR A Final Inspection by the FIRE Division is required gi Yes D No D This plan check review is NOT COMPLETE. Items missing or incorrect are listed on the attached checklist. Please resubmit amended plans as required. Plan Check Comments have been sent to: You may also have corrections from one or more of the divisions listed below. Approval from these divisions may be required prior to the issuance of a building permit. Resu/;>mitted plans should include corrections from all divisions. For questions OI' clarifications on the attached checklist please contact the ·following reviewer as marked: ~\\ <.: ::PLANN1NG" · '. : ,, . . .. . •. ·. \ · :: · 760:SQ24~10, , . : .. · ,;.'. ·:; '',; . . . . . ;-_.-:' D Chris Sexton D 760-602-4624 Kathleen Lawrence ~ Greg Ryan 760-602-27 41 760-602-4663 Chris.Sexton@carlsbadca.gov Kathleen.Lawrence@carlsbadca;gov Gregory.Ryan@carlsbadca.gov D Gina Ruiz 760-602-4675 Gina.Ruiz@carlsbadca.gov D Remarks: D D Linda Ontiveros 760-602-2773 Linda.Ontiveros@carlsbadca.gov D CindyWong 760-602-4662 Cynthia.Wong@carlsbadca.gov D Dominic Fieri 760-602-4664 Dominic.Fieri@carlsbadca.gov ~UijlDING DEP'f., COPY 11------'-----~----------~----'----------.. · Plan Review Requirements Category: TI , INDUST Date of Report: 07-23-2012 Name: Address: Permit#: CBl21347 DAVID BOYD FERGUSON PAPE ARCH. 4499 RUFFIN RD., #300 SAN DIEGO· CA 92123 Job Name: GENOPTIX: 510 SF TI OF EXJ:STIN Job Address: 1890 RUTHERFORD RD CBAD Conditions: Cond: CON0005562 [MET] ** CITY OF CARLSBAD FIRE DEPARTMENT -APPROVED: 1!-= Reviewed by: ___ '3-__ ~--- THIS PR,OJECT HAS BEEN REVIEWED AND APPROVED FOR THE PURPOSES OF ISSUANCE OF BUILDING PERMIT. THIS APPROVAL IS SUBJECT TO FIELD INSPECTION AND REQUIRED TEST, NOTATIONS HEREON, CONDITIONS IN . _ CORRESPONDENCE AND CONFORMANCE WITH ALL APPLICABLE REGULATIONS. THIS APPROVAL SHALL NOT BE HELD TO PERMIT OR APPROVE THE VIOLATION OF ANY LAW. ++ IF REVISIONS ARE REQUIRED BY OTHERS PLEASE MAKE THE FOLLOWING CORRECTIONS-- I. SHEET Tl.lUNDER "FIRE NOTES" DELETE THE REFERENCE "FHPS P-00-6" NOT CLEAR OF ITS MEANING.OR ORIG~, CERTAINLY NOT A CARLSBAD DOCUMENT. 2. FUTURE SUBMITTALS SHALL INCLUDE ACCURATE MPE LEGENDS. PLUMBING DOES NOT IDENTIFY 'MPG' AND IT IS ASSUMED THAT THIS IS 'Medium Pressure Gas'? Entry: 07/23/2012 By: GR Action: AP TECHNICAL REPORT HAZARDOUS MATERIALS SUMMARY For Genoptix, Inc. BioPharma Laboratory 1890 Rutherford Road, Suite 200 Carlsbad, CA 92008 March 15, 2012 tf)-1'7 ·~~~ ~ ~ f,l,t-l~ C-f::, 12..o 41 I Ill • -~ . OCCUPATIONAL SERVICES, INC. 7 Genoptix, Inc BioPharma Laboratory Technical Report l Hazardous Materials Summary OSl's CAS2Class Database used to Produce Technical Reports March 15, 2012 Page2 Occupational Services, Inc. ("OSI") owns a custom-designed Microsoft Access database that has been continually improved, updated and amended to reflect the current California Fire Code. Over 125,000 chemicals are currently recognized and classified by their Chemical Abstract Service Number (CAS No.) in OSI' s database, called "CAS2Class." The foundation of OSl's Technical Report is the Physical Hazard Summary an'd Health Hazard Summary reports produced by CAS2Class. Before presenting a Technical Report to a Code Official, OSI collects the .tenant's "proposed" chemical inventory and imports the inventory into CAS2Class. OSI then makes a proper hazard determination for every unclassified chemical. OSI uses trained and degreed HazMat professionals to determine the hazard categories, which are based on the chemical's Material Safety Data Sheet (MSDS), the manufacturer's product literature, and textbooks, along with the concentration, physical state, chemical properties .and health hazards of that chemical. OSI also refers to NIOSH, OSHA, EPA and DOT hazard classifications. OSI uses all these physical and chemical references to properly classify the chemical according to the categories listed in Appendix E of the 201 O California Fire Code (CFC). When 100% of the tenant's chemical inventory is properly classified, OSI generates these two tables: Physical Hazard Summary and Health Hazard Summary. OSI then compares the tenant's summaries to the Maximum Allowable Qµantity (MAQ) per Control Area of Hazardous Materials Posing a Physical Hazard listed in Table 2703.1.1 (1) & 2703.1.1 (3) of the 201 O CFC and the Maximum Allowable Quantity per Control Area of Hazardous Materials Posing a Health Hazard in Table 2703.1.1 (2) & 2703.1.1 (4) of the 2010 California Fire Code (CFC).. If the entire inventory does not exceed the MAQs, OSI advises the architect to design and construct one control area. If the MAQs are exceeded, OSI advises the architect to design more control areas until the inventory does not exceed MAQs. Many hours of technical expertise are spent designing the quantity and one-hour boundaries of the control areas. OSI and the architect use this CAS2Class report at the beginning of the design process and the information is used to form the basis of the building design. Genoptix, Inc. is a part of Novartis Molecular Diagnostics {MDx). a unit within the Novartis pharmaceuticals Division. They are focused on developing and commercializing evidence-driven tests to improve physicians' ability to optimize patient outcomes. Genoptix, lnc.'s BioPharma Services works to support clinical trials through full-service hematology/oncology testing·. Genoptix, Inc. esoteric laboratory combines a highly trained professional staff, experienced in hematomalignancies, with sophisticated instrumentation for optimal test efficiency and quality control. Genoptix, Inc., focus on providing high-level, personalized service to our clients to aid in a$say development, patient eli9ibility/stratification, efficacy endpoints, and lab results interpretation. Genoptix, Inc.'$ size and flexibiiity allows for creativity, customization, and responsiveness to help improve efficiencies as well as project outcomes. We offer multiple state-of-the-art technologies and draw on our staff of hematopathologists and Ph.D.s in order to deliver academic-level consultative services. These features allow us to ensure a collaborative, clinical protocol-and clinical literature- driven approach that is aligned with our client's goals. Genoptix, lnc.'s range of integrated technologies and services are provided in a centralized, CLIA-and CAP-licensed laboratory. Genoptix, Inc. is willing to go the extra mile to implement Pharma-developed assays inside a CLIA environment. Genoptix, Inc. has also established partnerships with international laboratories in order to support logistically challenging, global clinical studies. Genoptix, Inc BioPharma Laboratory Technical Rep9rt I Hazardous Material!? Summ~ry March 15, 2012 Page3 OSI and Genoptix, Inc. understand the Carlsbac;:I Fire Department will review this hazardous material opinion and technical Report and that the Building Official will request Carlsbad Fire Department's approval on this hazardous material opinion and Technical Report. A completed copy of this report will be submitted to the Carlsbad Fire Department: City of Carlsbad Fire Department .Fire Prevention Division 1635 Faraday Avenue Carlsbad, CA 92008-7314 www.firemail@carfsbadca.gov P: (760) 602-4665 F: (760) 602-8561 Executive Summary Genoptix, Inc. is submitting this Technical Report as part of a tenant improvement to remodel the existing BioPharma Laboratory located at 1890 Rutherford Road, Suite 200 in the city of Carlsbad CA, 92008. This Technical Report was .prepared by Jeffrey A., Silvers, Certified California Fire Code Inspector (CFC 0180.07), MPH, CIH, CSP (Curriculum Vitae attached), of Occupational Services, Inc. (OSI), 6397 Nancy Ridge Drive, San Diego CA 92121, and (858) 558-6736. This report includes: Building/facility infor.mation, Operational information and Hazaroous Materials information. None of the hazardous materials stored and/or l!Sed within tenant space (Control Areas) exceed the Maximum Allowable Quantity per Control Area of Hazardous Materials posing a Physical Hazard listed in Table 307.1 (1) or the Maximum Allowable Quantity per Control Area of Hazardous Materials posing a Health Hazard in Table 307.1 (2) of the 2010 California Building Code (CBC). Refer to Attachment 3 Physical Hazard Report Summary and Attachment 4 Health Hazard Report Summary shows the amounts hazardous materials stored and/or used. The Attachments coincide with Tables 307.1 (1) and 307 .1 (2) of the 2010 CBC. There are two control areas inside the building. Attached are the Physical Hazard (Attachment 3) and Health Hazard (Attachment 4) Report Summaries for Genoptix, Inc. BioPharma Laboratory (Control Area CA 1.1) listed below: · 1. Control Area One (CA 1.1, Suite 200 Occupied by Genoptix, Inc. BioPharma Lab) .2. Control Area Two (CA 1.2, Suite 100 Vacant) Based on the volum~ of hazardous materials on site, the design and operation of the building will be in compliance with the 2010 California Fire Code. Refer to Table 1 and Attachment 5 for detailed list of Chemical and/or Hazardous Materials stored and/or used by Genoptix, Inc. facility· located at 1890 Rutherford Road, Suite 200, Carlsbad CA 92008. Genoptix, Inc. will file the San Diego Regional Hazardous Materials Questionnaire DEH HM-9171 with the San Diego County Department of Environmental Health. Based on the proposed use of discloseable quantities of hazardous materials at 1890 Rutherford Road, Suite 200, Carlsbad CA 92008 Genoptix, Inc. will be required to submit a revised Hazardous Materials Business Plan. The plan according to the County DEH is required to be " ... submitted at least two weeks prior to scheduling your Final Inspection." Genoptix, Inc. will be calling for Final Inspection by Genoptix, Inc BioPharma Laboratory T~chnical Report / Hazardous Materials Summary March 15, 2012 Page4 the end of spring 2012·. Therefore Genoptix, Inc. has 90-120 days to complete the Business Plan. Genoptix, Inc. is not submitting a Business Plan at this time; however Genoptix, Inc. commits to submitting the Business Plan prior to final occupancy and understands that the Building Department will not grant a. final Certificate .of Occupancy until the San Diego County DEH processes our Business Plan. Table 1 of this Technical Report is a list of every chemical in Genoptix, Inc. facility inventory located at 1890 Rutherford Ro;:1d, Suite 200, Carlsbad CA 92008. The chemical inventory ilS sorted alphabetically, and then by Control Area. Included in Table 1 is the assigned hazard class from OSl's database. The majority of the inventory items have more than one hazard class. For example, Ethyl Alcohol is listed in Table 1 with three hazard classes, Flammable Class 1-B (F-IB) (chemical liquid has a flash point below 73 degrees Fahrenheit and boiling point of above 100 degrees Fahrenheit), Irritants (IRR) (acute chemical exposure irritates the skin), and Other Health Hazards (OHH) (chronic chemical exposure causes affect target organs of the human body: Liver, Kidneys, and Heart damage. Table 1 (Control Area 1) Paae-1 Genootix. Inc. BioPharma Lab Chemical lnventorv Use Storage Location Location % Control Control Area Chemical Name Hazard Class Cone. CAS# Qty Unit Area CA1.1 CA1.1 LABS 1701, LABS 1701, 1702, 1710, 1702, 1710, 1-BUTANOL F-IC IRR OHH 100 71-36-3 0.528 Gal 1717, 1804 1717, 1804 10% FORMALIN WASTE 92% WATER, 4% FORMALDEHYDE, 2% METHANOL, 2% SODIUM STORE STOREROOM POSPHATE) C3A, IRR, OHH, SEN Mixture 050-00-0 55 Gal ROOM 1402 1402 LABS 1701, LABS 1701, C3A, HTOX, IRR, 1702, 1710, 1702, 1710, 2-MERCAPTOETHANOL OHH 100 60-24-2 0.026 Gal 1717, 1804 1717, 1804 LABS 1701, LABS 1701, 1702, 1710, 1702, 1710, 2-PROPANOL F-IB, IRR, OHH 100 67-63-0 1.057 Gal 1717, 1804 1717, 1804 POST AMP POST AMP ALCOVE(-) ALCOVE(-) ARGON INERT GAS 100 7440-3M 336 Cft3 1805 1805 LABS 1500, LABS 1500, 1800, 1802, 1800', 1802, CIS-DIAMMINEPLATINUM HTOX,OHH,SEN 100 15663-21-1 · .055 Lbs 1805 1805 LABS 1500, LABS 1500, 1800, 1802, 1800, 1802, CIS-DIAMMINEPLA TINUM HTOX, OHH, SEN 100 15663-27-1 .0055 Lbs 1805 1805 LABS 1500, LABS 1500, 1800, 1802, 1800, 1802, ClOROX BLEACH IRR, OHH 100 7681-52°9 10 Gal 1805 1805 LABS 1500, LABS 1500, 1800, 1802, 1800, 1802, DIMETHYLSUPHOXIDE C3B, IRR, SEN 100 67-68°5 .026 Gal 1805 1805 LABS 1500, LABS 1500, 1800, 1802, 1800, 1802, D-MANNITOL IRR 100 69-65-8 0.111 lbs 1805 1805 LABS 1500, LABS 1500, DPBSWITHOUT CALCIUM 1800, 1802, 1800, 1802, AND MAGNESIUM IRR 100 . 7778-77-0 0.792 Gal 1805 1805 LABS 1500, LABS 1500, EAGLES MINIMUM ESSENTIAL 1800, 1802, 1800, 1802, MEDIUM. NH .100 000525-00-0 0.264 Gal 1805 1805 . LABS 1701, LABS 1701, 1702, 1710, 1702, 1710, ETHANOL 200PROOF F-IB, IRR, OHH. 100 64-17-5 8.456 Gal 1717, 1804 1717, 1804 LABS 1701, LABS 1701, 1702, 1710, 1702, 1710, ETHANOL DENATURED F-IB, IRR, OHH 100 64-17-5 4 Gal 1717, 1804 1717, 1804 Genoptix, Inc BioPharma Laboratory Technical Report / Hazardous Materials Summary March 15, 2012 Page5 Table 1 (Control Area 1 CA1.1) Page-2 Genootix Inc. BioPharma Lab Chemical lnvento1-v Use Storage Location Location % Control Control Area Chemical Name Hazard Class Cone. CAS# Qtv Unit Area CA1.1 CA1.1 LABS 1701, LABS 1701, ETHYL ALCOHOL FOR 1702, 1710, 1702, 1710, . MOLECULAR BIO F-IB, IRR, OHH 100 64-1-7-5 0.528 Gal 1717, 1804 1717, 1804 LABS 1500, LABS 1500, ETHYLENE GLYCOL M 1800, 1802, 1800, 1802, SOLUTION C3B, IRR, OHH 100 107-21-1 0.001 Gal 1805 1805 LABS 1701, LABS 1701, C2, CORR, TOX, 1702, 1710, 1702, 1710, FORMALDEHYDE, 36.5-38% OHH,SEN 36-38 50-00-0 0.396 Gal 1717, 1804 1717, 1804 LABS 1701, LABS 1701, FORMALDEHYDE, 37% C2, CORR, TOX, 1702, 1710, 1702, 1710, OHH, SEN 37 50-00-0 0.528 Gal 1717, 1804 1717, 1804 -LABS 1500, LABS 1500, C2, CORR, TOX, 1800, 1802, 1800, 1802, FORMALIN OHH,SEN 100 50-00-0 0.66 Gal 1805 1805 LABS 1500, LABS 1500, 1800, 1802, 1800, 1802, Gll.:L HEMATOXYLIN 1 IRR 100 517-28-2 0.132 Gal 1805 1805 LABS 1701, LABS 1701, ETHYL ALCOHOL FOR 1702, 1710, 1702, 1710, MOLECULAR BIO F-IB, IRR, OHH 100 64-17-5 0.528 Gal 1717, 1804 1717, 1804 LABS 1500, LABS 1500, 1800, 1802, 1800, 1802, GLYCEROL C3B, IRR, OHH 56-81-5 0.66 Gal 1805 1805 LABS 1500, LABS 1500, 1800, 1802, 1800, 1802, HEMATOXYLIN IRR 517-28-2 0.132 Gal 1805 1805 LABS 1500, LABS 1500, 1800, 1802, 1800, 1802, HEPES BUFFER (1M) IRR 7365:45-9 . 0.078 Gal 1805 1805 LABS 1701, LABS 1500, 1702, 1710, 1800, 1802, HYDROCHLORIC ACID 1.0N CORR 7647-01-0 0.264 Gal 1717, 1804 1805 LABS 1701, LABS 1701, 1702, 1710, 1702, 1710, HYDROCHLORIC ACID 2 MOL CORR 7647-01-0 0.264 Gal 1717, 1804 1717, 1804 LABS 1500, 1800, 1802, LIQUID CARBON DIOXIDE CRYOINERT 000124-38-9 95.2 Gal 1805 PCR (Nl 1800 LABS 1500, 1800, 1802, LIQUID NITROGEN CRYOINERT 0007727 °37-9 47.6 Gal 1805 PCR (N) 1800 LABS 1500, LABS 1500, 1800, 1802, 1800, 1802, METHYLPARABEN IRR 99-76-3 0.111 lbs 1805 1805 LABS 1500, LABS 1500, 1800, 1802, 1800, 1802, MOUNTING MEDIUM IRR OHH 100 000881-00-0 24 Ounces 1805 1805 LABS 1500, LABS 1500, PHOSPHAT BUFFERED 1800, 1802, 1800, 1802, SALINE SOLUTION IRR 100 7778-77-0 0.022 lbs 1805 1805 LABS'1500, LABS 1500, PHOSPHAT BUFFERED 1800, 1802, 1800, 1802, SALINE SOLUTION IRR 100 7778-77-0 0.132 Gal 1805 1805 LABS 1701, LABS 1701, 1702, 1710, 1702, 1710, SHUR/MOUNT F-IB IRR, OHH 100 108-88-3. 0.5 Gal 1717, 1804 1717, 1804 Genoptix, Inc BioPharma Laboratory Technical Report/ Hazardous Materials Summary Table 1 (Control Area 1 CA1.1.) Paae-3 Genontix March 15, 2012 Page6 Inc. BioPharma Lab Chemical lnvento1-v Use Storage Location Location % Control Control Area Chemical Name Hazard Class Cone. CAS# Qtv Unit AreaCA1.1 CA1.1 LABS 1701, LABS 1701, SODIUM HYDROXiDE 1702, 1710, 1702, 1710, SOLUTION CORR,WR1 100 0001310-73-2 0.26 Gal 1717, 1804 1717, 1804 LABS 1500, LABS 1500, 1800, 1802, 1800, 1802, · TRYPSIN WITH EDTA 1X · IRR,OHH 100 9002-07-7 0.156 Gal 1805 1805 LABS 1500, LABS 1500, 1800, 1802, 1800, 1802, TWEEN20 C3B, IRR 100 9005-64-5 0.13 Gal 1805 1805 LABS 1500, LABS 1500, 1800, 1802, 1800, 1802, WATER BATH SOLUTION IRR, OHH 100 12125-02-9 118 Ounces 1805 1805 Table 1'. 1 Reference Table for (Hazard Classifications and Class Codes listed in Table 1) --,, --, ·, 'I ! · HAZARD:CLASSIFICATION CLASS•CODE ·HAZARD,CLASSIFICATION _ 1 CLASS CC:>DI:'. ,, - COMBUSTIBLE LIQUID CLASS II C2 FLAMMABLE SOLID FS COMBUSTIBLE LIQUID CLASS IIIA C3A HIGHLY TOXICS HTOX COMBUSTIBLE LIQUID CLASSIIIB C3B INERT GAS, GAS OR LIQUIFIED INERT-GAS COMBUSTIBLE FIBER (LOOSE) CFL IRRITANTS IRR COMBUSTIBLE FIBER (BALEDl CFB NON-HAZARDOUS NH CONSUMER FIREWORKS · (CLASS C•COMMON) 1.4G CFW1.4.G ORGANIC PEROXIDE UD, I THRU V OP-(UD THRU Vl CORROSIVES CORR OTHER HEAL TH HAZARDS OHH CRYOGENIC FLAMMABLE CRY,0-FLAM OXIDIZER CLASS 1THRU 4 OX-(1 THRU 4) CRYOGENIC INERT CRYO-INERT _ OXIDIZER GAS, GAS OR LIQUIFIED OX-GAS CRYOGENIC OXIDIZING CRYO.OX PYROPHORIC PYRO EXPLOSIVES'1.1 thru 1.6 EXP-(1.1-1.6) RADIOACTIVES RAD FLAMMABLE GAS FG SENSITIZERS SEN FLAMMABLE LIQUID CLASS IA FL-IA TOXICS_ TOX FLAMMABLE LIQUID CLASS IB FL-IB _UNSTABLE (REACTIVE) 1 THRU 4 UR-(1 THRU 4) FLAMMABLE LIQUID CLASS IC FL-IC WATER REACTIVE 1 THRU 3 WR-(1 THRU 3) FLAMMABLE LIQUID CLASS COMBINATION (IA 18 IC) FL-(IA,I8 IC) Table 2 indicates total Maximum Allowable Quantity (MAQ) per Control Area of hazardous material posing a Physical Hazard that is. stored and/9r used in Genoptix, Inc. (BioPharma Lab Control Area One CA1.1) per 2010 CFC Table 2703.1.1(1) Table 2 (Genootix, Inc. BioPharma Lab Control Area One CA1.1) QUANTITY. ·STORED 1ln '%OF :MAQ PER:2'010 CFC '':MAQ --' Control,Ariia:one :MAT.ERIAUCLASSIFICATION ' TABLE 2703.:1.1:(1) -. ·CA1.1 , ·USED. 1MAGl':AlloWable'lrlcrease -_ _ COMBUSTIBLE LIQUID CLASS II 480 Gallons 1.584 Gallons 0.33% 478.416 Gallons/99.67% COMBUSTIBLE LIQUID CLASS IIIA ·1320 Gallons 55.026 Gallons 4.17% 1264.974 Gallons/95.83% COMBUSTIBLE LIQUID CLASS 1118 26,400 Gallons 0.817 Gallons 0.0031% 26399.183 Gallons/99.9969% COMBUSTIBLE FIBER (LOOSE) None In this Control Area N/A. N/A N/A ; ' Genoptix, Inc BioPharma Laboratory Technical Report/ Hazardous Materials Summary March 15, 2012 Page? Table 2 (Genoptix, Inc. BioPharma Lab Control Area One CA1.1) Continued ' ---' ' -%:0F. '' MAQ PER 210 CFC , , QUANTITV'.~T0Rl;:Q · ·MAQ 'MATERIAUCtASSIFICATl0N TABLE 2703.1.1 (1) · ·In Control.Area,One : ,USED· ,MAQ·:A11owable1lricrease_ COMBUSTIBLE FIBER {BALED) _ None In this Control Area NIA NIA NIA CRYOGENIC FLAMMABLE None In this Control Area NIA NIA NIA CONSUMER FIREWORKS {CLASS C COMMON} 1.4G None in this Control Area NIA NIA NIA CRYOGENIC OXIDIZING None In this Control Area NIA NIA NIA EXPLOSIVES 1.1 thru 1.6 None In this Control Area NIA NIA NIA FLAMMABLE GAS None in this Control Area NIA NIA NIA .FLAMMABLE LIQUID CLASS IA None In this Control Area NIA. NIA NIA FLAMMABLE LIQUID CLASS IB 480 Gallons 14.541 Gallons 3;03% 465.459 Gallonsl96.97% FLAMMABLE LIQUID CLASS IC 480Gallons 0.528 Gallons 0.11% 479.472 Gallonsl99.89% FLAMMABLE LIQUID CLASS COMBINATION (IA, 18 IC) 480 Gallons 14.069 Gallons 2.931% 465.931 Gallonsl97.069% FLAMMABLE SOLID None In this Control Area NIA NIA NIA INERT GAS, GAS OR LIQUIFIED Not Annllcable 336 Cft3 NA Not Aoolicable _ CRYOGENIC INERT -Not Aoollcable 142.8 Gallons NA Not Annlicable ORGANIC PEROXIDE UD I THRU V None in this Control Area NIA NIA NIA OXIDIZER CLASS 1THRU 4 None In this Control Area NIA NIA NIA OXIDIZER GAS, GAS OR LIQUIFIED None in this Control Area NIA NIA NIA PYROPHORIC None in this Control Area NIA NIA NIA UNSTABLE {REACTIVE} 4 None in this Control Area NIA NIA NIA UNSTABLE (REACTIVE) 3 None In this Control Area NIA NIA NIA UNSTABLE {REACTIVE) 2 None in this Control Area NIA NIA NIA UNSTABLE {REACTIVE} 1 None in this Control Area NIA NIA NIA WATER REACTIVE 3 None in-this Control Area NIA NIA NIA WATER REACTIVE 2 None In this Control Area NIA NIA NIA WATER REACTIVE 1 Not Aoollcable .260 Gallons NL Not Limited Table 3 indicates total Maximum Allowable Quantity (MAQ) per Control Area of hazardous material posing a Health Hazard that is stored and/or used in Genoptix, Inc. BioPharma Lab (Control Area One CA 1.1) per 201 Q CFC Table 2703.1.1 (2) Table 3 (Genootix, Inc. BioPharma Lab Control Area One CA1.1) '' QUANT-ll'Y %OF ,, . • MAQ PER 2010 CFG STORED· ijrj ',NiAQ ·, MATERIAU,CLASSIFICATION TABLE 2703.1.1 (2) Control Area One : ;USED .. _ 'MAQ AIIQwable-ln·crease . • CORROSIVE SOLID Lbs None In this Control Area _NIA NIA NIA CORROSIVE LIQUID Gals 2000Galloris 2.372 Gallons 0.119% 1,997.628 Gallons 199.881% HIGHLY TOXICS SOLID Lbs 40 Pounds. 0.055 Pounds 0.1375% 39.945 Pounds 199.8625% HIGHL y TOXICS LIQUID Gals 40Gallons 0;026Gallons 0.065% 39.974 Gallons 199.935% TOXICS SOLID Lbs None-In this Control Area NIA NIA NIA TOXICS LIQUID Gals 2000-Gallons " 1.584 Gallons 0.0792% 1,998.416 Gallons 199.9208% Genoptix, Inc BioPharma Laboratory Technical Report I Hazardous Materials Summary March 15, 2012 Page8 Bulking and Dispensing of Hazardous Materials/Wastes: Bulking and/or dispensing of Hazardous Materials Class I Flammable, Class II. and Clas~ Ill, Combustible Liquids will occur in the designated Genoptix, Inc (BioPharma Lab Control Area One CA 1. 1) locations as listed in Table 4. Bulking and/or dispensing of Hazardous Waste Liquids will occur in the, designated Genoptix, lnc·Control Area One locations as listed in Table 4. Glass and/or Plastic 250-500 milliliter containers will be used to dispense Hazardous Materials Class I Flammable, Class II and Class Ill, Combustible Liquids within the fume hoods of designated bulking and dispensing locations listed in Table 4. 5 gallon (UL) listed and/or (FM) approved Polyethylene/Metal safety containers will be used for bulking Class I Flammable, Class II and Class Ill, Combustible Waste Liquids will occur in (Control Area One CA1 .1) Storage Room (1402) as listed in table 4. 5 gallon Storage Room (1402) is equipped with a Nederman Snorkel which captures flammable and/or harmful vapors during the bulking and/or dispensing process. Glass and/or Plastic 250-500 milliliter containers will be used to dispense Hazardous Materials Class I Flammable, Class II and Class Ill, Combustible Liquids within the fume hoods of designated bulking and dispensing locations listed in Table 4. 5 gallon (UL) listed and/or (FM) approved Polyethylene/Metal safety cans wili be used for bulking Class I Flammable, Class II and Class 111, Combustible Waste Liquids in Control Area One (Storage Room 1402). 5 gallon (UL) listed and/or (FM) approved Polyethylene/Metal safety containers will be properly grounded during bulking and/or dispensing operations. The maximum quantity of liquid waste that will be bulked and/or dispensed at one time is a :S 5 gallon (UL) listed and/or (FM) approved Polyethylene/Metal safety container. Refer to Table 4, which lists all locations where Hazardous Materials and/or Hazardous Wastes will be Bulked and/or dispensed within the Genoptix, Inc BioPharma Lab located at 1890 Rutherford Road, Suite 200, Carlsbad CA 92008. Bulking and/or Dispensing of Class I Flammable, and Class II, and Class Ill, Combustible Liquids will occur in the following locations: Table 4 (Bulkina and Dispensing Area Locations in CA 1.1) ROOM ,. NUMBER. · ·ROQM:NAME · CON:J1ROL1AREA .. ,,, I .. • l 1402 STORAGE ROOM. 1402 CONTROL AREA 1 CA 1.1 1701 LAB 1701 CONTROL AREA 1 CA 1.1 1702 LAB 1702 CONTROL AREA 1 CA 1.1 1710 · LAB 1710 CONTROL AREA 1 CA 1.1 1717 SUPPORT 1717 CONTROL AREA 1 CA 1.1 1804 .POST(-) AMP 1804 · CONTROL AREA 1 CA 1.1 Hazardous materials including, Oxidizing, Reactive, Water Reactive, Highly Toxic, Corrosive, Caustic, and Pyrophorics will be stored in hazardous materials storage cabinets. Doors will be well fitted, self-closing, and equipped with a latch. The hazardous materials storage cabinets will meet the construction standards in 201 o CFC 2703.8.7. 1. Table 5 lists all Hazardous Materials that will be bulked and/or dispensed in Control Area One; Quantities to be bulked and/or dispensed, and types of containers used during bulking and/or dispensing. (Note: Only :S 5 gallons of flammable and/or combustible Liquid will be bulked and/or dispensed· during any bulking and/or dispensing operation). Genoptix, Inc BioPharma Laboratory Technical Report/ Hazardous Mat~tials Summary March 15, 2012 Page9 Table 5 {Control Area One CA1.1) A Complete Ust of Hazc;1.rdous Materials to be bulked and/or dispensed in (Control Area One CA1.1 (USE-OPEN) (NO-USE-CLOSED USE;QPEN _. · ,;yp~ c;ontarn,r'fdr --.. _ . _ P,1aterlaU Bulklng/Dlspensl11g · · Quantlllesito,be -i -Trailsfqr/Dl9peljslng,Clas~JI-& ',HAZARDOUS MATERIAL. Classification -l:.ocat1on1C:A1 .1 'Bulked/Dispensed -·. _.cIass,II;FIammabiail.:lqulds ,_ 1 Gallon /500 Milliliter Container LABS 1701, 1702, dispensed into 250-500 Milliliter FLAMMABLE 1710,1717,1804 Glass/Plastic Container, Glass 1-BUTANOL LIQUID CLASS IC ·Fume Hoods S 1 Gallon Tube / Beaker. 10% FORMALIN WASTE 5 Gallon (UL) Listed (FM) 92% WATER, 4% Approved Safety Can FORMALDEHYDE, 2% Bulked/Dispensed into 55 METHANOL, 2% SODIUM COMBUSTIBLE Gallon DOT approved Metal POSPHATE) LIQUID CLASS IIIA Storage Room 1402 S5Gallon Drum 1 Gallon /500 Milliliter Container LABS 1701, 1702, dispensed into 250-500 Milliliter FLAMMABLE 1710, 171.7, 1804 Glass/Plastic Container Glass 2-PROPANOL LIQUID CLASS IB Fume Hoods S 1 Gallon Tube / Beaker. 1 Gallon /500 Milliliter Container LABS 1701, 1702, dispensed into 250-500 Milliliter FLAMMABLE 1710, 1717, 1804 Glass/Plastic Container, Glass ETHANOL LIQUID CLASS IB Fume Hoods s 1 Gallon Tube / Beaker 1 Gallon /500 Milliliter Container LABS 1701, 1702, dispensed into 250-500 Milliliter FLAMMABLE 1710; 1717, 1804 Glass/Plastic Container, Glass ETHYL ALCOHOL LIQUID CLASS IB Fume Hoods S1 Gallon Tube / Beaker ..• 1 Gallon /500 Milliliter Container LABS 1701, 1702, dispensed into 250-500 Milliliter COMBUSTIBLE 1710, 1717, 1804 Glass/Plastic Container, Glass FORMALIN LIQUID CLASS II Fume Hoods S 1 Gallon Tube / Beaker 1 Gallon /500 Milliliter Container LABS 1701, 1702, dispensed into 250-500 Milliliter COMBUSTIBLE 1710, 1717, 1804 Glass/Plastic Container , Glass FORMALDEHYDE 37% LIQUID CLASS II Fume Hoods S1 Gallon Tube / Beaker 1 Gallon /500 Milliliter Container LABS 1701, 1702, dispensed into 250-500 Milliliter SHUR/MOUNT FLAMMABLE 1710, 1717, 1804 Glass/Plastic Container, Glass (TOLUENE) LIQUID CLASS IB Fume Hoods S1 Gallon Tube / Beaker Table 6 and Table 6.1 include MAQ of In-Use Open Systems permitted in (Control Area One CA 1.1) c;1nd allowable increases as per 2010 CFC Tables 2703.1.1 (1) and 2703.1.1 (2). Table 6 {Control Area One CA1.1) bulking and/or dispensing Control Area One CA1.1) USE- OPEN per 2010 CFC Table 2703.1.1(1). MAQ PER2010 -:MAQ Allowab.leJncrea~e ·- CFC TABLE , 2703.1.1 (1)(In-QtlAN:tlTY (I~-Use : ' Use Open . Open) Control Area . MATERIAUCLASSIFICATION .svstem) ,one·CA1.1 ,_ --,_ .. -. .- COMBUSTIBLE LIQUID CLASS II 60 Gallons S2Gallons S 58 Gallons/96. 7% COMBUSTIBLE LIQUID CLASS IIIA 160Gallons S5Gallons S 155 Gallons/96.875% FLAMMABLE LIQUID CLASS 1-A,IB,IC 60 Gallons S5Gallons S 55 Gallons/91.7% ' Genoptix, Inc BioPharma Laboratory Technical Report / Hazardous Materials Summary March 15, 2012 Page 10 Tabl~ 6.1 (Controi Area One CA1.1) bulking and/or dispensing (Control Area One CA1.1) USE- OPEN per 2010 CFC Table 2703.1.1(2). MAQPER2010 ; 'MAQ AllowalSI~ Increase--' ',, CFC TABLE .2703.1.1 (2) (In-' -QUANTITY;(ln-Use Use,Open Open),Control-Area : -- :MATERIAL/C~SSIFICATION .. S.vstem\ OneCA1.1 '. --·-,'; . ' ' CORROSIVE (LIQUID) 100 Gallons :S 2 Gallons _ :S 98 Galloils/98% Building/Facility Information The ,building is located at 1890 Rutherford Road, Carlsbad; CA 92008 is a Type 111-8 fully Sprinklered building. The building is two $tories with a total square footage of (60,096 ff I floor). Genoptix, Inc Bio Pharma Lab will remodel only (8,560 ff) of the original -building Suite 200 (Control Area One CA 1.1) under this proposed tenant improvement. Attachment tis a copy of a Vicinity Map Project Site location for the Genoptix, Inc. BioPharma Lab Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008 Attachment 2 is a copy of the Genoptix, Inc. BioPharma Lab Tenant Improvements Title Sheet Drawing T1 .1 prepared by Ferguson Pape Baldwin Architects for Genoptix, Inc. BioPharma Lab Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008. Attachment 2.1 is a copy of the Control Area Plan T1.5 prepared by Ferguson Pape Baldwin Architects for Genoptix, Inc BioPharma Lab Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008 showing First Floor Gontrol Area Plan and Second Floor Area Plan. Attachment 2.2 is a copy of the First Floor Control Plan of Control Area Plan T1 .5 prepared by Ferguson. Pape Baldwin Architects for Genoptix; Inc BioPharma Lab Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008 showing First Floor Control Area Plan and Bulking and/or Dispensing locations listed in table 4. Attachment 2.3 is a copy of the Second Floor Control Plan of Control Area Plan T1 .5 prepared by Ferguson Pape B.aldwin Architects for Genoptix, Inc BioPharma Lab Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008 showing Second Floor Control Area Plan. (Note: No Hazardous Materials and/or Wastes will .be stored and/or used on second floor of this building in (Suite 200 Control Area One CA1.1) Operational Information The building located at 1890 Rutherford Road, Suite 200, C~rlsbad CA 92008 consists of three occupancy classifications. The building is "A-3, B, S-1" (60,096 ff) occupancy, with two control areas. Genoptix, Inc. BioPharma Lab will occupy Suite 200 Control Area One CA 1.1 (23,666 ff) of the building. Suite 200 First Floor is (20, 129 ff), and Suite 200 Second Floor is (3,537 ff·). for a total combined space in Suite 200 of (23,666 ff) The "A-3" occupancy (Lunch and/or Meeting Room) in this building Suite 200 (Control Area One CA 1.1) is (1,048 ff) which is less than 10% of area of the story (20,129 ff) Suite 200 (Control Area Two CA1.2) (36,430 ff) is vacant. The building consists of approximately 60% laboratory function and/or suppQrt and 40% administration and/or logistic support. Genoptix, Inc. BioPharma Lab provides services to support clinical trials through full-service hematology/oncology testing. Genoptix, Inc. esoteric laboratory combines a highly trained professional staff, experienced in hematomalignancies, with sophisticated instrumentation for optimal test efficiency and quality control. Genoptix, Inc. focus on providing high-level, personalized service to our clients to Genoptix, Inc BioPharma Laboratory Technical Report/ Hazardous Materic:11s Summary March 15, 2012 Page 11 aid in assay development, patient eligibility/stratification, efficacy endpoints, and lab results interpretation, using typical laboratory quantities of hazardous materials. Based upon the proposed volume and usage of hazardous materials, the proper occupancy classification of 1890 Rutherford Road, Suite 200, Carlsbad CA 92008.is "A-3,·B, and S-1." The entire building consists of two control areas (Suite 200 Control Area One CA 1.1) and (Suite 200 Control Area Two CA 1.2). There will be primary bulking and dispensing of (Class I Flammable, and Class II, Class Ill-A Combustible liquids) within furn~ hoods of Lab 1701, Lab 1702, Lab 1710, Support 1717, and Post(-) AMP 1804. Bulking of hazardous waste will occur in Storage Room1402. Use of(Class I Flammable, and Class 11, Class Ill-A Combustible liquids) will occur only in designated bulking and dispensing areas and/or laboratories. Hazardous materials and wastes will be restricted to the designated bulking and dispensing areas and/or laboratories. Designated .bulking and dispensing areas and locations are listed in Table 4. For detailed information concerning both the physical and health hazards at 1890 Rutherford Road, Suite 200, Carlsbad CA 92008, please refer to the enclosed three chemical classification reports Attachments ~' 4 and 5. These reports are based on the (2010 California Building Code Table 307.1 (1) & Table 307.1 (2) and 201 O California Fire Code Table 2703.1.1 (1) & Table 2703.1.1 (2)). None of the hazardous materials exceed the exempt amounts for physical or health hazards for storage or use. The following controls will be installed at 1890 Rutherford Road, Suite 200, Carlsbad CA 92008 1. Automatic Fire Extinguishing System for buildings (2010 CFC 903.2, NFPA 131 The building is fully equipped with an existing, approved, automatic wet fire extinguishing ·system. 2. Seismic Bracing and Shelf Construction for hazardous materials. [2010 CFC 2703.9.9] Shelves greater than six feet high will be braced and anchored and be of substantial construction. Shelves will be provided with lips or guards. The laboratory will be equipped with adequately braced and anchored shelving of substantial noncombustible construction with a chemical resistant coating. Shelves will be provided with a lip or guards. Shelf storage of hazardous materials will be maintained in an orderly manner and in compliance with the Code. 3. Separation of Incompatible Materials [2010 CFC 2703.9.8] Incompatible materials will be separated from each other in storage in (FM) approved self- closing storage cabinets, or in separate (UL) listed or (DOT) approved waste collection containers. To ensure compliance, one or more of the following methods will separate incompatible materials: • Storage in separate approved· self-closing storage cabinets as follows: . ~ Flammable/Combustible liquids (Class I, II, and Ill-A) will be stored in approved flammable liquids cabinets, • Acids will be stored in acid cabinets, • Bases will be stored in base cabinets. • Trained personnel will further distinguish between incompatible materials (i.e. acids and bases; oxidizers and flammables; acids and flammables) and store them in an appropriate m~nner with adequate distance to avoid incompatible reactions. • · Incompatible gases will be separated by a distance of more than twenty feet • Incompatibles will be separated using noncombustible partitions/barrier greater than 18" Genoptix, Inc BioPharma Laboratory Techni9al Report/ Hazardous Materials Summary high. March 15, 2012 Page 12 Employees will receive chemical safety instruction on the separation of incompatible materials. 4. Empty Containers [2010 CFC 2703.2.5] The storage of empty containers and. containers previously used for the storage of flammable or combustible liquids, unless free from explosive vapors, will be stored as required for filled tanks and containers. Tank and containers, when emptied will have the covers or plugs immediately replaced in openings. 5. $ecurity [NFPA 730 & NFPA 731] The building will be equipped with lock(s) to prevent unauthorized entry, security cameras and motion detectors. The security measures in place at 1690 Rutherford Road, Suite 200, Carlsbad CA, 92008 are within compliance of the Code. 6. Fire Extinguishers [2010 CFC 906.1 & NFPA 654 6.2.2] The facility will be equipped with portable dry chemical fire extinguishers. There will be an appropriate amount of approved fire extinguishers mounted not more than 75 feet apart within the Genoptix; Inc. facility, located at 1890 Rutherford Road, Suite 200, Carlsbad CA 92008 which is (23,666 ft'}. The appropriate amount and type fire extinguishers will be located throughout the building; designated dispensing areas and laboratories. 7. Approved Flammable Liquid and Hazardous Materials Storage Cabinets [2010 CFC 3404.3.2] Flammable and combustible liquids will be stored in approved flammable liquid storage cabinets. Doors will be well fittea, self-closing, and equipped with a latch. 8. Laboratory Fume Hoods and Building Ventilation and Exhaust Systems and Types of Material Exhausted a. Flammable Gases and Vapors in the Exhaust Systems. The ventilation system at Iris Chemistry Center will consist of galvanized duct in varying size from 1 O" round duct to 24" x 24" rectangular di.Jct, which is exhausted to a utility fan located on the roof. Scientists will be trained not to exhaust incompatibles into the ventilation systems. This galvanized duct is suitable for the bench scale laboratory reactions performed in the fume hoods at Iris Chemistry Center and is in compliance with the Code of Federal Regulations Volume 29 Part 1910.1450. The storage and use of flammable and combustible liquids and gas~s in hoods and exhaust ducts will be limited to the smallest amounts needed each day. Concentrations of gases and vapors will be diluted to less than 10% of the lower explosive limit (L.E.L.) for each compound. Therefore, no automatic fire protection systems will be required in the fume hoods or exhaust ducts. b. Corrosive and Oxidizing Materials Corrosive and oxidizers will be used in the chemical fume hoods. Corrosives will be neutraiized in the chemical experiments and the corrosives will not be exhausted untreated directly into the fume hoods at concentrations that could attack the ducting or accumulate and drip. The corrosives are used in milliliters quantities for pH adjustment and not at original strength nor heated and exhausted untreated where they could attack the ducting. Genoptix, Inc BioPharma Laboratory Technical Report/ Hazardous Materials Summary March 15, 2012 Page 13 Therefore no special ducting or treatment is needed. Oxidizers will be used in the fume hoods and consumed or decomposed in the chemical reactions and not be available to release oxygen or react with organics in the exhaust system. c. Heating The materials being exhausted will not be heated above standard room temperature. Mechanical exhaust will be provided where Class I, 11, or Ill liquids are used (in any amount) in Group B, or portions thereof. Under normal operating conditions explosive vapor-air mixtures will not develop in the exhaust system at Genoptix, Inc. The majority of the work involving Class I, II, or Ill-A flammable liquids will be performed in chemical fume hoods, not in the open laboratories. The exhaust ventilation will be s1,1fficient to maintain non-flammable and non- explosive vapor concentrations throughout the entire exhaust duct system. Genoptix, Inc. activities will not require elevated temperatures. Therefore, separate and distinct exhaust systems are not required. d. Calculations to determine necessary CFM required to maintain levels <10% and 25% LEL for Class I, 11, Illa-A Flammable liquids Hoods and Building Exhaust Systems and Types of Material Exhausted Calculations to Determine Required CFM to Maintain Levels <10% and 25% LEL for F.lammable Liquids The follpwing report contains calculations for the volume of air in cubic feet per minute (CFM) required to dilute flammable liquid vapors to 10% and 25% or below their lower explosive limit. These calculations represent a spill scenario in which a one-gallon container of flammable liquid was to shatter in fume ,hood, releasing the entire contents. The calculations are based on the release being vaporized consistently for a one-hour period. Table 7 Flammable Liquids Stored at Genoptix, Inc. BioPharma Lab 1890 Rutherford Road, Suite 200 Carlsbad CA 92008 " Fl~mmable/Combustlble , ,Molecular Specific • ;Lower Explos·ive ' . -( ·Vapor' ,Liauid ,Weight , .Gravity ,':Limit Density 1".BUTANOL 74.12 0.84 1.4 2.56 2-PROPANOL 60.1 0.785 2.5 2.1 ETHANOL 46 0.78 3.3 1.5 FORMALDEHYDE 30.02 1.08 6 1.03 TOLUENE 92.05 0.9 1.1 3.1 Calculating the Required CFM The following calculations were made to determine the minimum ventilation required to assure that the aforementioned flammable liquids are. maintained below 10% and 25% of the Lower Explosive Limit. Requirements were based on the cubic feet of air required per gallon of evaporation. The calculation used was taken from NFPA 86 "Standards for Ovens and Furnaces", section 7-5.2 Method for Determining Solvent Safety Ventilation Rates. CFM to maintain <10% LEL = 10( 833 )(SpGr)(IOO-LEL) I . 0.075 VD LEL 160mm Genoptix, lnG BioPharma Laboratory Technical Report I Hazard.ous Materials Sur:nmary CFM to maintain <25% LEL = Where: 4(~)(SpGr)(lOO-LEL) / . 0;075 VD LEL 160mm 10 = Safety Factor to Account for 10% LEL 4.0:;: Safety Factor to Account for 25% LEL 8.33 = Weight of 1 gallon of water 0.075 = Weight of dry air in 29.9 in. Hg SpGr: Specific gravity VD = Vapor Density LEL = Lower Explosion Limit March 15, 2012 Page 14 Table 7.1 is a worst-case scenario in which the CFM calculated was to account for a gallon of flammable liquid being released in a fume hood over a one hour period. Table 7.1. Minimum Required Ventilation in CFM to maintain concentrations of Flammable Liquids below 10% Lower Explosive Limit (LEL) during a one-gallon spill situation released over a one-hour . d per10 ·tta at 10% Required ·CFM to maintain. l :Flammable/Combustl.ble Llauld .LEL/G . 'belaw 10% U~Lfor one·.ih0ur _: I 1-BUTANOL 24781 413 2-PROPANOL 16192 270 ETHANOL 16924 282 FORMALDEHYDE 18245 304 TOLUENE 28991 483 Table 7.2. Minimum Required Ventilation in CFM to maintain concentrations of Flammable Liquids below 25% Lower Explosive Limit (LEL) during a one-gallon spill situation released over a one-hour . d oer10 . fta at25% • ·Requii:e-d,CF-M ,to ·.maintain ,,, ' Flammable/Combustlble-Li.auid LEUG below 25% LEL:1for ooe ... hour 1-BUTANOL 9915 165 2-PROPANOL 6477 108 ETHANOL 6770 113 FORMALDEHYDE 7300 122 TOLUENE 11'600 193 The worst case scenario spill for the flammable liquids stored in a fume hood at Genoptix, Inc. facility is a one gallon release of TOLUENE. To ensure that such a spill be maintained at 10% the lower explosive limit, fume hoods must provide an airflow of a minimum of 483 cubic feet fresh air, per minute. All of Genoptix, Inc. BioPharma Lab fume hoods will exhaust more than 483 CFM. Since the exhaust volumes will be greater than 483 CFM;. the duct work is NOT classified as Product .Conveying Ducts. Genoptix, Inc BioPharma Laboratory Technical Report I Hazardous Materials Summary 9. Sources of Ignition [2010 CFC 3404.2.4] March 15, 2012 Page 15 In locations where flammable vapors could be present, precautions will be taken to prevent ignition by eliminating or controlling sources of ignition. Adequate grounding and bonding will be provided to prevent the accumulation of static electricity wherever Class I or II liquids are bulked and/or dispensed. Smoking and open flames will be prohibited in locations where flammable vapors could be present. 10·. Compressed Gases [2010 CFC 3001.1] Storage, use and handling of compressed gas containers_, cylinders, tank and systems shall comply with the 2010 CFC Chapter 30. Partially full compressed gas containers, cylinders or tanks containing residual gases shall be considered as full containers for the purposes of the controls required. Compressed gases in service and in storage will be stored upright and adequately secured with one or more support straps and/or chains to prevent cylinders from fallihg or being knocked over. Cylinders, including empty ones, will have their caps in place and valves tightly closed. Cylinder will always be secured. Cylinders will only be moved by Genoptix, Inc. employees with an approvec:I cylinder cart and/or dolly. The storage, use and handling of compressed gases atGenoptix, Inc. shall be in accordance with the 2010 CFC Chapter 22, 26, 27, 30, 35, 37, 40, 41 and the NFPA 52. 11. Cryogenic Liquids [2010 CFC 3201] Storage, use and handling of cryogenic fluids shall comply with the 201 0 CFC Chapter 32. Cryogenic fluids classified as hazardous materials shall also comply with the 201 O CFC Chapter 27 for general requirements. Partially full containers containing residual cryogenic fluids shall be considered as full containers for the purposes of the controls required. Oxidizing cryogenic fluids, including oxygen, shall comply with NFPA 55 and the 2010 CFC Chapter 40. Flammable cryogenic fluids, including hydrogen, methane, and carbon monoxide shall comply with NFPA 55 and the 20-10 CFC Chapters 22 and 35. Inert cryogenic fluids, including argon, helium and nitrogen, shall comply with CGA P-18. Cryogenic fluid storage tanks and/or vessels, including empty ones, will have their caps in place a'nd valves tightly closed. Cryogenic fluid storage tanks will always be secured. Cryogenic fluid storage tanks and/or vessels will only be moved by Genoptix, Inc. employees with an approved cylinder cart and/or truck designed for secure movement of the container. The storage, use and handling of cryogenic fluids at Genoptix, Inc. shall be in. accordance with the 2010 CFC Chapter 22, 27, 32, 35, 40 and the NFPA 55. 12. Spill Control, Drainage, Secondary Containment [2010 CFC 2704.2.1, 2704.2.2, & 2704.2.2.1] Carts c;1rid trucks transporting liquids shall be capable of containing a spill from the largest single container transported. Genoptix, Inc. BioPharma L~b will never store vessels containing hazardous materials greater than 55 .gallons or exceed a total of 1000 gallons. The vessels exceeding 1.1 gallon capacity in the (designated bulking and/or dispensing areas and laboratories) used for flammable liquids will be equipped with secondary containment. Genoptix, Inc BioPharma Laboratory Technical Report /Hazardous Materials Summary 13. Explosion Control [2010 CFC 2705.2.1.2] March 15, 2012 Page 16 Oxidizers, unstable reactive compounds, and water-reactive compounds will be stored in approved explosion proof or flammable liquid caoinets. The explosion controls will be in compliance with the 2010CFC Sections 911, & .2704.6. 14. Limit Controls [2010 CFC 2705.1.4] temperature Controls will be maintained in the event of a power failure. Temperature controls will be in compliance with the Code. Pressure controls are not applicable. Genoptix, Inc. does will not store stationary tanks onsite. 15. Treatment Systems [TITLE 22 CCR CH-12 ARTICLE-1 {66262.10] Genoptix, Inc. will properly manage any hazardous waste generated at 1890 Rutherford Road, Suite 200, Carlsbad CA 92008 in accordance with Federal State and Local regulations. 16. Protection from Vehicles [2010 CFC 312] Currently Genoptix, Inc. BioPharma Lab stores all Hazardous, Materials inside the building and any vehicle impact protection needed will be in compliance with the 201,0 CFC 312. 17. Employee Training and Response Procedures/Hazard Communication [2010 CFC 406, 2010 CFC 407, and Title 8 CCR §5194] Persons responsible for the operational of areas in which hazardous materials are stored, bulked, dispensed, handled, or used shall be trained initially and annually on the chemical hazards of the materials and the appropriate spill mitigation procedures. The supplied training will be in compliance with 2010 CFC 406, 2010 CFC 407, and Cal/OSHA Title 8 CCR §5194. Genoptix, Inc. has provided Cal/OSHA compliant Hazard Communication safety training course and will continue to provide refresher courses every year. The following information is taught to each hazrnat employee in the building: In the event of a FIRE: First, notify local fire d~partment by dialing 911 from a landline when possible, versus a mobile phone. Next, if possible, have an employee trained on the proper use of a fire extinguisher extinguish the fire with an ABC fire extinguisher. If the fire cannot be 1 extinguished safely with one extinguisher, evacuate all personnel from the building. SMALL SPILL: Use the emergency spill kits compatible with the spilled materials. Refer to Material Safety Data Sheets (MSDSs) for protective clothing and clean up guidelines. Waste products will be handled and disposed of as hazardous Waste. LARGE SPILL: Secure the area and warn others away. Contact Jennifer Sullivan Facilities Manager. (760} 268-6472 to develop a clean-up plan. Call the Fire Department if the spill .represents a fire hazard or hazardous materials ate released outside of the building. Arrangements will be made with a waste disposal firm such as lnqenium Environmental Services for assistance with cleanup and disposal of hazardous wastes. 18. Storage of Hazardous Materials [2010 CBC Table 307.1 (1) & Table 307.1 (2) and 2010 CFC Table 2703.1.1(1) & Table 2703.1.1 (2)] Genoptix, Inc BioPharma Laboratory Technica.1 Report/. Hazardous Materials Summary March 15, 2012 Page 17 No hazardous materials are stored in quantities greater than the exempt amount for "B" and "S- 1" Occupancy. No hazardous materials will be stored and/or used in "A-3" occupancy or on second floor of this building. All hazardous materials will be stored in (FM) approved and/or (UL) Listed self-closing safety cabinets or containers. Hazardous Materials Information The at~ached chemical classification report is based on 2010 CBC Tables 307.1(1) and 307.1(2) and the 2010 CFC Tables 2703.1.1 (1) and 2703.1.1 (2). None of the hazardous materials exceed the Maximum Allowable Quantities (MAQs) for Physical or Health Hazards for storage or use. The report identifies hazardous materials by chemical name. All classifications were based on hazard categories delineated in 201.0 CFC Appendix E "Hazard Categories." Aggregate quantities of each hazardous material and each hazard category have been specified. Materials have been identified as: in use, open system use, closed system use. The aggregate quantity in use and storage shall not exceed the quantity listed for storage. I certify that all information contained herein, including the attachments, is true and correct. I have authority to act on behalf of and bind relative to matters involved in this Technical Report. A copy of my Curriculum Vitae is attached (Attac;hment 6) along with a copy of current certification as a Certified California Fire Code Inspector from National Code Services Association (Attachment 7). I certify that all information contained herein, including the attachments, is true and correct. I have authority to act on behalf of and bind Genoptix, Inc. relative to matters involved in this Technical Report. Approved: Jeffrey Silvers, MPH, CIH, CSP Vice President 6397 Nancy Ridge. Drive San Diego, CA 92121 Tel: 858-558-6736 Fax: 858-558-6756 Genoptix, Inc BioPharma Laboratory Technical Report/ Hazardous Materials Summary Attachment 1 March 15, 2012 Page 18 Attachment 1 is a copy of a Vicinity· Map Project Site location for the Genoptix, Inc. BioPharma Lab Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008 VICINITY MAP FARA AV£. • . Qenoptix M·e~ic;:d LabQrat9ry-~ipPh.~rma. Lab Project Site· LocaJipn 1890 Rutherford Roa~,. ~µJt~ D Carlsbad CA 92008 PROJECT SITE Genoptix, Inc BioPharma Laboratory Technic"'I Repqrt I Hazardous Materials Summary Attachment 2 March 15, 2012 Page 19 Attachment 2 is a copy of the Genoptix, Inc. BioPharma Lab Tenant Improvements Title Sheet Drawing T1 .1 prepared by Ferguson Pape Baldwin Architects for Genoptix, Inc. Bio Pharma Lab Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008. f GENOPTIX MEDICAL LABORATORY I BIOPHARMA LAB TENANT IMPROVEMENT VICINITY MAP { 1890 RUTHERFORD ROAD, SUITED CARLSBAD, CA 92008 f ARCHITECT: FERGUSON PAPE BALDWIN ARCHITECTS f MECHANICAL ENGINEER: i ELECTRICAL ENGINEER: f GENERAL CONTRACTOR: I MECHANICAL SUB,CONTRACTOR: f ELECTRICAL SUB-CONTRACTOR: l i PROJECTDIRECTORY .sHrolNDEX . WALSH ENGINEERS MPE CONSULTING GOQD & ROBERTS INC, PACRIM MECHANICAL ICKLER ELECTRIC BUlDING DATA ...... TITl.6,Z4 IIANDA10RY illVl!I.DPI! REQUIRDIENTI J.i»c"IIMt~HJH..t,Mctd:WtMIJl rcr1,fM.WMl«'Jt1:1£11<J,1!:Jfill.1CU11JrBJ.IH~ ~~~===:tJW~~TA.S.V. "-IU.t:.tt.V)X,li'HOMililMPf'JWUKl.1,,i.1ll ~ff1~,l,lll'f1'Af.:M.~--ltfff .. 1f'"9') ~"*~lt.\D,,:DS .. ,f'~l'fl':ID Ml!MAMNIUl.attiuk:tt~M,_ ' FLOOR AREA ANALYSIS •mr eeermettetmtw ,_ ---.._,1,urwt'l"'1Ynw:u, ,...,.ii,,l., ·"·"" ......... N.1t\ltllUIINbblJ.Jhl.._ • .,MitffitHUJ,-t Jmll-MJ.alW..IWm;ri.~~1-lll'.,._f.1.31 .IWIIM{t-tewJI¥;, BUILDING CODE DATA ~ IUU$l~'!l'IU:iaFUIU"411/U. ... uhohU,l .. p;u._. u,.u. .. ,....u.c .. -----R, ;ltl:UN'"* ... ~Tl.tUl,H."'lh"ll'lhl¥1.oilllW ~"ff-Tl. ~'"""'"1'1*'11'1!•1lv.,,.,.,,...,.,.,.. ..... ltillJN...,.01111h.li~f•lll1,1,t,, ~~-...... ,~~"'J"l,1-11.u, In .. , ... ,,, _____ fti(ll.'ti~"t ................ DE!AILED SCOPE OF WORK STRUCTURAL NOTES ELECTRICAL NOTES .. ___ ,,..... __ ""' ... ,,..,_... •• ,. .. "T .. ..,._,_ MECHANICAL NOTES "il•t-..i ... _,...._, .. ,".-".~ "ll"W'.1""'1"1""~1'!\l,...1"'f"Mt~-H..._,,.~~t FIRE NOTES t. :..~J!~~~1='!.';!!..~",:'~'',!,'3,!~-~--.i1t,-.:ai:1AA; "..,., ... _ra<UOO-t~•-1'~,.-W-"'-'"'"-~..,.,.,.,.,."- ,. ~...:i:t~:~.;:l~""ftl'•".lf"''"')'fl~,W. .. l.-,r-cP1'P•• .. ~---+·-·-++-•·----tl'II I 1M1 er klrr 1te&t11•6Jet+tzte STOAII WA'IU Ql!All1Y NOTESCOH$1RIICTIOII IIW$ ~~Hl.olll~llfM1lllll.tlllU'tlli.tr9"11.t! .. HIWl¥ ..... ll:ll,t"u.>~I\WMl.- '\~=fi''f'!WTIW,,UMIIANrM1•IWlnl~M'l¥JO,.-.M:~Jn ,~ 40tf1Jt,ibw 11.ttm ~tip t,\UtJt l'Ul11R1 ...,....~~ I :;;;"' .... -----· l ~n.t $Int T1.1 Genoptix, Inc BioPharma Laboratory Technical Report/ Hazardqus Materials Summary March 15, 2012 Page 20 Attachment 2.1 Attachment 2.1 is a copy of the Control Area Plan T1 .5 prepared by Ferguson Pape Baldwin Architects for Genoptix, Inc BioPharma Lab Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008 showing First Floor Control Area Plan and Second Floor Area Plan. i ! i I it ! i i t I I ; i I f J I i I i i f I I l I • I f } I i .BJ...j.-........... ""-11,-oioll.i..;-.i+,..-fillill--~---0 <b 6) FIRST FlOOR CONTROL AREA P~N l;i;~,t--=. =,~=-=-----~-----------8 I i ·-·-·-·-·-·-r-·-·-·-·-·-·-·-·-·-·-· -·-@ i @tm,'.,,i-,!._=ECOH=,,,=,_?..-FL_OOR_CON_TR_OL_mA __ PLA_N ___________ a 44,,Mlhtll at•m tll1Cl,p CA.t:m '1tl.UUU IIW'll",t,,a,.1'""" G . ' I IC<tiTROt.. ~-5 Genoptix, Inc BioPharma Laboratory Technical Report/ Hazardoµs Materials Suillmary Attachment 2.2 March 15, 2012 Page 21 Attachment 2.2 is a copy of the First Floor Control Plan of Control Area Plan T1 .5 prepared by Ferguson Pape Baldwin Architects for Genoptix, Inc BjoPharma Lab Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008 showing First Floor Control Area Plan and Bulking and/or Dispensing locations listed in table 4. LAB 170~ POST(·) AMP 1804 LAB 1710 AATCHEll AA"..AREPRE$ENTS 2ND FLOORA'EZZA'\1NEOFSEPA'IA1E 'TEw.NT·!?ACla/lllO'll;~,~ AREA 1,t, UNOERSl:l!;OF CECKAN~ AU. CCI.U,'NS'!IEAMS TD i;i; \',\Ml'PEC \\1Tll 'IYl'll 'J<: G'Yf11UM UO.•RllTOPRO'mcAHlRR/ITING, elCISTIHG\\'Al.WAAECURREHTLY. IJ~IL'r10A1 flollRAATING, SUPPORT 1717 @ FIRST FLOOR CONTROL AREA PLAN T1 ~ S;CA1E1 ~in,.1'·11" ' cb -----------------------" ------------------------------------------- Genoptix, Inc BioPharma Laboratory Technical Report/ Hazardous Materials Summ~ry Attachment 2.3 March 15, 2012 Page 22 Attachment 2.3 is a copy of the Second Floor Control Plan of Control Area Plan T1 .5 prepared by Ferguson Pape Baldwin Architect$ for Genoptix, Inc BioPharma Lab Located at 1890 Rutherford Road, $uite 200, Carlsbad, CA 92008 showing Second Floor Control Area Plan. (Note: No Hazardous Materials and/or Wastes will be stored and/or used on second floor of this building in (Suite 200 Control Area One CA1.1) I ~F· ==raa=lll!"""'iiirr""'!!!:=:a-·-·-·-·-·-·-1-·-·-·-·-·-·-·-·-·-·-·--·--@ I I . ,.... ,.. /--,... /" ar;r·off 1r" , ti r , , I I I I I , 2M I L7 1 L, I L7. I L7 I L7 L...1. LI L • .1. L....i. · L-1. -CONTROL ARE.AJ 1.1 !~ I I I i°:!:i! ~::~e; wm· e-!--. -. -. -............... ~l!Biii:iiE---~tilliiiii:ii~ii;iii:iiw~----.-:a1. -. -8 -I I I e e e ~ @ !~:~FLOOR CONTROL AREA PLAN --------------No Hazardous Materials are stored and/or used on the Second Floor of this building Genoptix, ·inc BioPharhla Laboratory Technical Report/ Ha~ardous Materials ;3ummary Attachment 3 (Page 1 of 3) Physical Hazard Report Summary for Genoptix, Inc BioPharma Lab March 15, 2012 Page 23 Control Area One CA1.1 Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008 Genoptix. Inc. BioPhanna Laboratory, 1890 Rutherford Road, Suite 100, Carlsbad CA 92008 Physical Hazard Report Summary :Mulaam.Wnrible Quudty per Coatro!Ara of Hazanlom l\latcrlalPosmc I Pliyslc11H11.1rd S-qe U se-OC11ed Syttmas Uae-OpmSyttans llATERIAL/CLAs.s Solill •s Liljuill Gas Sold Jbs Lilj11il Gas Solid •s Liquid (cs.ft.) ••••• (cs.ft {cu. ft.) 11&•s (cu.It. (aa.ft.) plons {Jbs) lilNTI') (Jbs} @NTP) ~sl Location Coard Area CAt .1 COMBUS1IBLH UQUID CLASS II 0.000 l.S84 0.000 0.000 0.000 0.000 0.000 2.000 _COMBUS1IBLH UQUID CLASS Ill-A 0.000 55.025 0.000 0.000 0.000 0.000 0.000 S.000 COMBUS1IB!.H·UQUID CLA.SS 111-B 0.000 0.117 0.000 0.000 0.000 0.000 0.000 0.000 COMBUS1IB!.H l'!Bl!lltOOSBl!ALED 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 CRYOOBNICFtAMMAlltB 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 CONSUMD.l'!Rl! w~s CLASS C 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 COWONl.40 Cll-YOGl!NJC OXJDIZING 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 BXPLOSIVESDMSION l.1 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 BXPLOSIVESDMIJION.1.2 9.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 BXPLOSIVESDMSIONl.l-0.000 ·0.000 0.000 0.000 0.000 0.000 0.000 0.000 BXPLOSlVESDMSION l.4 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 BXPLOSIVESDMSION 1.40 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 BXPLOS!Vl!SDMSIONl~ ·o.ooo 0.000 0.000 0.000 0.000 0.000 0.000 0.000 Tlnnday,?.ruth 15, 2012 Pait lof3 Genoptix, Inc BioPharma Laboratory Technical Report/ Hazardous Materials Summary Attachment 3 (Page 2 -of 3) Physical Hazard Report Summary for Genoptix, Inc BioPharma Lab March 15, 2012 Page24 Control Area One CA1.1 Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008 Genoptix, Inc. BioPharma Laboratory3 1890 RutherfordRoad, Suite 100, Carlsbad CA 92008 Physical Hazard Report Summary l\fulan.m..rillle Qlutlty ;er ColllrolArea tlH11211rdo1a M1ted1lP01lag 1Pllyslc11Hazard seora,ie u .a.e.i 8.)·Jtenn U~pmSysen1s l\lATERIAL/CLASS Solli•s U.•W Gas Soldlb Liljuill Gas SoW•s Liquid (ca.ft) pion (cu.ft. (m.ft.) gallons (cu, ft. (ru. ft.) galons {lbs) (i).NrP) (Jiu) (i).NfP) (lu) BXPLOSIVBSDMSION 1.6 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 FLAMMAIIL1l OASOASl!Ol/S 0.000 0.-000 0.-000 0.000 0.000 0.000 0.000 0.000 IlQUIFIBD FI.AMMABLl!IlQU1Dct.,ss1~, 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 FLAMMABµ!IlQUlD CLASSI•B 0.000 14.S~l 0.000 0.000 0.000 0.000 0.000 0.000 FI..WMABUI IlQl:1D CLASSI-C 0.000 0.SlS 0.000 0.000 0.000 0.-000 0.000 0.000 COMBINA1IONFLAMMABLB 0.000 15.069 0.000 0.000 0.000 0.000 0.000 S.000 IlQl:1D 1A lB IC INmiTOAS, GASEOUS 0.000 0.000 336.000 0.000 0.000 0.000 0.000 0.000 FLAMMABLI! SOilD 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 CRYOO!!NI_C INBRT,IlQUBl'IED 0.000 142.100 0.000 0.000 0.000 0.000 0.000 0.000 OltG..'INlCPl!ltoXIDBSCUSSUD 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 ORGANIC PBllOXIDBS CLASS! 0.000. 0.000 0.000 0.000 0.000 0.000 0.000 0.000 OR.O.OOC ;R!R.OXIDBS cussn 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 OR.O.~ICPBR.OXIDBS CLAssm 0.000 0.000 0.000-0.000 0.000 0.000 0.000 0.000 OR.O.~IC PBllOXIDBS CLASS IV 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 OR.G.ANIC'.A!R.OXIDBSCLASSV 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 Tburaday, Muth.15, lOU Pa11lo!3 Genoptix, Inc BioPharma Laboratory Technical Report/ Hazardous Materials Summary Attachment 3 {Page 3 of 3) Physical Hazard Report Summary for Genoptix, Inc BioPharma Lab March 15, 2012 Page 25 Control Area One CA1.1 Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008 Oenoptix, Inc. BioPharma Laboratory, 1890 Rutherford Road, Suite 100. Carlsbad CA 92008 Physical Hazard Report Summary Mu .... Annra•leQaatll)'.per CoatrolArea afHazanlo .. MaterJuP01ing a PhysicalHazarll s.on.e U 111-C1aed Systems Use-Opea Systems l\lATIRIAL/CLASS Solii ., ti.aid Gas SoldJh L]IJ1&id Gas Solid Its Liquid (c-.ft) plons (cu.ft (m.ft.) galllns (cu.ft. (m.ft.) plons (Ills) lilNil') (Dul (a)NTP} {DIS) OXID!Zl!R. CLASS-4 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 OXID!Zl!R. CL.\S53 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 OXID!Zl!R. CLASS2 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 OXID!Zl!R. <;LASS I 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 OXID!Zl!R.GASGASl!OUSUQUIFll!D 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 PntOPH!>lUC 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 UNSTABLE (RllCllVE) CLASS-4 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 UNSTABLE (Rl!ACllVE) CL.\SSJ 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 UNSUBLE (RB,\CllVE) CUSSl 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 UNST..mLE {Rl!.\Cl!VE) CLASS 1 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 WATBIUIEAC1IVE CLASS3 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 WATBRRE!\CllVE CL.\SS2 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 WATBRREACIIVI! CLASS 1 0.000 Q:l® 0.000 0.000 0.000 0.000 0.000 0.000 Tllllrlday,MuthlS,2012" Genoptix, Inc BioPharma Laboratory Technical Report I Hazardous Materials Summary Attachment 4 (Page 1 of 1) Health Hazard Report Summary for Genoptix, Inc BioPharma Lab March 15, 2012 Page26 Control Area One CA1.1 Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008 Genoptix, To.c. Bioi>harmaLaboratory, 1890 Rutherford Road, Suite 100, Carlsbad CA 92008 Health Hazard Report Summary Location Coatrd Area CAt.1 St.,..e Use-Cilletl S},ttms " Use-Open ~•eim lfATIRIAL/CLASS Soldiis LJ.taW Gas Solid•• Litjulol Gas Solid lbs Llqllld (e& It) plloas (CL ft (ca. ft.) ,a11o •• (aa.lt. (cu. ft.) ploas ~I) @NTl') <•s) {i)NTP) (lbs) COllOSIVES 0.1)1)D 2-372 OJlOO OJlOO OJlOO OJlOD 0"000 lDOO HIGHLY TOXICS OJ)55 Ml6 ODOO 0.000 0.1)1)0 0.000 MOO OJ)OO TOXICS 0.000 1.514 0.000 0.000 0.1)1)0 0.000 MOO 0.000 T11unllly,Man:h U,l0U P•Jt!ofl Genoptix, Inc BioPharma Laboratory Technical Report I Hazardous Materials Summary Attachment 5 (Page 1 of 7) March 15, 2012 Page27 Detailed Chemical Inventory Report Summary for Genoptix, Inc BioPharma Lab Control Area One CA1.1 Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008 Inventory Report for Genoptix, Inc. BioPhannaLaboratory, 1890 Rutherford Road, Suite I 00, Carlsbad CA 92008 .Location ControlArea CM.1 Class: COMBUSI1BLELlQUJD CLASS 11 (IJQWDS) c.a-CA!ilt tfait Qllnfir Qmnlity ii Galbn ~ 31::S.;1% .zo«l-0 Ga1 0.396 0396 ~3'?% ~-0 Git O.S:lS O.SlS 10llW.IN ,0-0D-O Go1' 0.,HO 0.66!1 S'llftmllY:farGidlalll (3 dniilfCOfdt) S.a Class: COMBUS11BLE.UQUJD CLASSlll-A (LIQUIDS) .5.S.000 :5:5.0M Class.-COMBUS11BLE UQUID CLASS 111-B (LJQtJ1DS) ·CJla• CA!ilt UJlit Qaufiy Qm:ntilf ii Galbn DJM!THYLStlHIOJl!Dl! IMH ,d 100.000 0.0.M :!T!mZNI! a. YCOL M Sa.ur.DN 101-:21-1 Got 0..001 0.001 GL'!re!lOL .56-11-.5 Ga1 Mftl M6!l nn.NlO ~~~ Got CU:50 0.130 S.......yforGolloas (4 dllollfCOfdt) Saa Ul1 Genoptix, !nc BioPharma Laboratory Technical Report I H_azardous Materials Summary Attachment S (Page 2 of 7) March 15, 2012 Page 28 Detailed Chemical Inventory Report Summary for Genoptix, Inc BioPharma Lab Control Area One CA1.1 Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008 Location Class:_ CORROSIVES (IlQUIDS) Cull.II CAS# UDit Qumiy Qllilnlily:ill Gall>:n ~'311.5-31% ,0-00.() Gal 0395 ?~31¼ ,0,00.() Gal 0.5:!! O.SlS l'OllWJN .50-0:,.() Gal 0.6® HYCltocm.at:c &:ID_LON 1641-01.() Gid 0264 HYCltOCHI.<llE .~ID::U,IOL 1647-01.() Go1 0-264 S<Dlll?,llMllOXlD!:JOLUitON 0001310-13·:2 Gal 0-260 S........yf«Gdlom (f"9tiillfll:Ofds). Class: CRYOGENIC LVERT, LIQUEFIFJJ (llQUIDS) '41.600 '4'1.600 S.a lU.10D Class: FJ,AMMABLELIQUlD CLASS I-B (LIQUIDS) Cail-CASIII UDit Qu;aatiy ·Qllilulily:ill G.illl:l:n :2-PltCPAmL 61-63.() Go1 1.05] LOS7 fflUNOL :200Plt001' . 6HH GIi U55 S-455 fflUNOLIEUTtlt!D 54-17,5 Gd '4..000 '.!TH'4. AICOH:>L 101 llOD!:Ctl..llBJJ 5HH Get' O.Sl! O.SlS SBlttiMOtlN!' lOWta Gal o.500 S,aram,y.!«Gdlom {5 .t.ll'il«<X>tdt) S.a l.f..~l Class: .FLAMMABLELIQUID CLASSI-C (LIQUIDS) UDit Quatiy Qllilutily :ill Gillll:n lla!flof7 Genoptix, Inc BioPharma Laboratory Technical Report/ Hazardous Materials Summary Attachment 5 (Page 3 of 7) March 15, 2012 Page 29 Detailed Chemical Inventory Report Summary for Genoptix, Inc BioPharma Lab Contro.l Area One CA1.1 Loc~ted at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008 IAcation ControlArea CAI.1 Class: FLAMMABLELIQUJD CLASSI-C (LIQWDS) Cu• CA!lt U:ilit Quanliy ·Qualllily iDGilbn l·BOl'ANOL '.11'36'3 Go! U1S o.m :S~Gollom {l detail<ll>Clfd) :s.. 05?8 Class: HIGHLY TO)(ICS(LIQUIDS) en~-CA!ifl. Vat Qumiy Qamtily ill Gllll>n :l-M!EAPron'HAN:>L f0.24-:2 Go! 0.026 M\26 :S~Gollom {l<ltllllilrtCCINI) :s.. 41.ffl ·Class: HIGHLY TOXICS (SOLID) en .. CA!lt lhlit Quanliy Qmutily:iDLbs. CJS-~ 15HH7-l ~ 25.000 W.5 ClS-~ 1560-ZH q 25.000 rum :SwamryEo<llll.(2 d41ailtell0fdl) :S.• 0.4155 Class: JNFlff GAS, GASEOUS (GAS) en. CA!ifl\ Ullit QRanliy ·Qualltily :iD Cu. Ft. AIGON '.M40·S7-l Cfl3 336.000 336.000 :S~C'A.:ft{ldulfflll!d_) :s.. :Ud.000 Class: lRRJTANIS (LIQ'(JIDS) c.-CA9¥ Ullit QRlllfiy QualllilyilG~U,n 10¼ l'OllWJNWAST!9l% WATD. 4% 00»00~ Go! .5.5.00~ :5;5.000 1-BOl'ANOL 11'36.a Got G:5:lS o.5lS :l-:m:ICJPTon'R.\N)L f0i14-:l Gel 0.016 MM :l-PltCP.\mL j'.1-0-0 Gol L0.51 L0.51 ~M&'ck l.5.::011 PaJe3of'7 Genoptix, Inc BioPharrria Laboratory Technical Report/ Ha;zardous Materials Summary . Attachment 5 (Page 4 of 7) March 15, 2012 Page 30 Detailed Chemical Inventory Report Summary for Genoptix, Inc BioPharma Lab Control Area One CA1.1 Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008 Location ControlA.na CAJJ Class: lRRIT.ANTS (LIQUIDS) C.aae CA!l# Unit Qaa:ntiy 'Qualltily :ill G.alln1 CIOIOXBI,'!.\ffl 76Sl-'1-9 q.1 10.000 10.000 Dl1tl!Tm!L~ 67~1,5 ,rd 100.000 MU mBS'l\.ih<111t.:eamllllhmJ11ai11112. ms-m Gil 0.7:lll o.m :!THANOL ::OOPJr.car 6H1'5 Go! U.56 U.56 :!'I'HANOL Ill!NAl'Ul!D f4e.l:i-,5 God 4.000 4.000 D'H"4.Al£0HJL 101.lmll!CU..\I.JSD f4e.11-.5 Go!. o.m 0..'15 ~ a. '1roOL »sa.m.DN lOi-21·1 Go! 0.001 O.ODl GlLLlEU'IOJl."UlN l .511-2:S-2 Go! 0.132 0.132 GL'Yt:l!:m:t. .55'11-.5 ·Gil o.660 o..650 Hl!W,'ICllM.N .517~1'1 Go! 0.132 o.m Ifl!lEi JSt.Wl!1{W) 13~.5~ Go! runs O.OiS PBJSPHJ:t' JSU'l.!llD s.u;m sa.urD ·1ns-11-o Go! 0.132 0.132 SBOl'..'1dOUN!' lOUH Get MOO o..m N!:!NlO 9005'54-.5 Get· 0.13-0 0.130 S~Gallam {lSdmailHll>l'<h) ha :82.11.11 Class: IRRIT.AJ.VIS (SOLID) c.-CA!l# Unit Qaa:ntiy Qanlify :iaLbs. D-mDllno1 S-d5..C lbs 0.111 0.111 ~AUJS:!N 99-16.a lbs 0.111 0.111 PIDSPH.U' JSU'll!Jl!D S.\LJN!: Sa.Ul'D 1111'11-0 lbs 0.022 O.Oll w~'1'!1:SA'llUa.urDN . UW-ol-9 0 4.000 O.z:l Slln:ll'al}"t«lln. {UtllilrRl!dl) . s •• ,om Class: NON HAZARDOUS (LIQUIDS) CAa-CA!l# Unit Qaa:ntiy Qantily :ill Gilll>:a 'I'lmr.tda.)! Msdl l.5. l012 Pli!•4oi'.1 Genoptix, Inc BioPharma Laboratory Technical Report/ Hazardous Materials Summary Attachment 5 {Page 5 of 7) March 15, 2012 Page 31 Detailed Chemical Inventory Report Summary for Genoptix, Inc BioPharma Lab ContrQI Area One CA1.1 Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008 Location Control.Area CA.1.1 Class: NON HAZARDOUS (LIQUIDS) CASI¥ ~\<Z.UMOOMW J!SS!Nl'I.U.lll!D. OOQill-OO-() S'llnlml}'f«Gollom (l odetllllffGOfd) Class: OIHFlJ.HEALTH HAZARDS (LIQUIDS) C.ame C.~9¥-Unit Qlli:atiy 10¼10llllL!NWAST.!!ffl4 W.tl'D,.f¾ ~-00-0 Gill SJ.000 1-Jru'XANOL 71-i36'3 Gel o.s:s 'l-Ml!l.C.W1'0El'IUNJL ~-;2 Gill 0..0:& ::-PllCP.ANJL -61-0-() Gel LOY.I !'l'HANOL l'OOPl.001 64--11~ G!1 U.56 ~IJ!N.'I.TtUD ,64-1'1-.5 Gal -4.000 !:l'lm.AICOfl)L :fOX:r.lOll!CtLlllSD -M-11-:5 Gal o.s::s :!THU!.N!~YOOL MSa.Ul'DN 10:i:-:1-1 Gel 0.001 1'~56..S<>I¾ .50-00-() Got '0:596 1~3)'% ,50«)-() Ga1 o.s:s lont.'ILIN .50-00-() G'e1 M60 GL>'CDOL .56'81-:5 Ga1 U-60 S~-'MOUNl' 101-1"3 Gel 0..500 TJ.'YPSINwm!ml'.'I. 1X 900M1-1 <lat 0.1.56 S'llnlml}'f«Gellom (14 dellll remrdl) Swa Class: OTHER.HEALI1I HAZARDS (SOLID) e:na .. CAS!t Ullit Qilalltiy CJS-~ 1.5§6-::7-1 pm 25.000 CJS-~ 1.56'3'-::7-l q 25.000 »oUNIINGMmt.M 'OOOHl-00-() 0 ::+.000 'l'lnnda]r :U.di 1.5.1-01: Qaallfily il ~D .55..000 o.m 0.0!6 LOS7 :U.56 --4.000 0..51S 0.001 0396 o.m o.no M60 o..soo 0.1.56 1W6 QailJlfily il Lbs. 0.05.5 0.000 1-SOO l'Ji.!1•, .. f1 Genoptix, Inc BioPharrna Laboratory Technical Report I Hazardous Materials Summary Attachment 5 (Page 6 of 7) March 15, 2012 Page 32 Detailed Chemical Inventory Report Summary for Genoptix, Inc BioPharma Lab Control Area One CA 1.1 Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92008 " ' Location Control.Area C.A.1.1 Cldss: 011IER.HEALTH HAZARDS (SOLID} CJaame CA!l¥ Ullit Qaut.iy Qmnlily ill Lbs. w.nn:u:msa.tn'DN U~4 0 .+.000 0.:50 S~:U,,.{t <lai!fllCDfdl) ha I.IDS Class: SENSIIlZER.S (LIQUIDS) eu-CAS#c Ullit Qua:atiy QiimlilyillGilll:n 10%70DWJNWAST.!9l% \'aTD,4% o:»>00-0 Glil .5.5..000 !i.5..00!) DlM!TH'n.Stll'HOl!ID!: . ·U-IS.,S ,d 100.000 0.0:6 1~35..531% .50-00-0 Gil 0396 0.:-96 1~31% .50-00-0 Get O.!ilS O;SZS fOllULIN .50-00-0 Gd 0.6~ 0.-650 :Slllllllll}'f«Godloas (5<1111ai! ........ ) S.• :56.flO Class: SENSIIlZER.S (SOLID) CJaame CA!l¥ Ullit ·Qaaufiy Qa,autily :ii Lbs. ClS·DI.~JN01,l 1.56~·21-l !GI" 15.000 0.055 ClS·Dtua.mnr..fflNtlK 1.566-21-l q 15.000 0.000 S~:U,,.{l<lllailfllCDfdl) s.. 11.tDSS Class: TOXICS (IJQUIDS) em-CA!l¥ Ullit Quaufiy Qmntily:ilGilll:n ~~;,5,;1¼ ,!,Q-00-0 Gil. 0.396 0396 1~3'1% .50-00-0 Gil. o.,zs oxs lOllfALIN :50-00-0 Gil. u~ U50 SlllrlmfY!«Oo1lom (3<1111ai!nc<>rdt) :S,,a 15U 'IlnndayldzGh l!i,::OU Pa,!ll60f'.1 Genoptix, Inc BioPharma Laboratory Technical ReportJ Hazardous Material~ $ummary Attachment 5 (Page 7 of 7) March 15, 2012 Page 33 Detailed Chemical Inventory Report Summary for Genoptix, inc BioPharma Lab Control Area One CA1.1 Located at 1890 Rutherford Road, Suite 200, Carlsbad, CA 92Q08 CiJntrolA.rea CA.1.1 Class: WATERREA.CTIVECLASS 1 (LIQUIDS) Smllll,l ·Hl.'DI.OXlDI! 501.tmON SDlmlll,YforGaflom {l dNil """"'6) CAS# Genoptix, Inc BioPharma Laboratory Technical Report/ Hazardous Materials Summary Attachment 6 Curriculum Vitae for Jeffrey Silvers, MPH, CIH, CSP EDUCATION March 15, 2012 Page 34 Masters of Public Health, Industrial Toxicology, Graduate School of Public Health, San Diego State University, 1992. Bachelor of Science, Health Sciences, Option: Industrial Hygiene, California State University Northridge, 1986. CERTIFICATES AND REGISTRATIONS Certified Industrial Hygienist, AmericanBoard of Industrial Hygiene, Certificate No. 5833. Certifiecl Safety Professional in Comprehensive Practice, Board of Certified Safety Professionals, Certificate No. 13326. ADDITIONAL TRAINING ASTM Technical and Professional Training on the Environmental Site Assessments, April 2002. OSHA 40-Hr HAZWOPER Training 1991 and current with 8-Hour Refresher Training. Factory Trained at Laconic to Test, .Repair, and Certify Biolog.ical Safety Cabinets, 1997. PROFESSIONAL HISTORY .Occupational Servic.es, Inc. (1994 to Present) Mr. Silvers is Vice President and Director of Occupational Services, Inc. (AOSI=) in San Diego, CA. Mr. Silvers manages a staff of sixteen environmental engineers, industrial hygienists and health physicists who provide environmental compliance, industrial hygiene, spill clean-up, radiation safety, biological safety and chemical safety services to clients in California. The services provided by OSI include environmental permitting, environmental site assessments, property transaction screens, indoor air quality, industrial ,hygiene sampling for organics, metals, dusts, asbestos, radioisotopes, and biological contaminants, radioactive materials licensing, sealed source leak tests, and radiation detection instrument calibrations. Mr. Silvers has extensive environmental management experience in performing environmental site assessments and environmental compliance audits. He has managed client's hazardous, radioactive, and. Bioha?:ardous waste, prepared hundreds of haza(dous materials business plans, industrial discharge permit applications, and chemical classification reports to building, fire, and planning departments. Mr. Silvers has been the point of contact during regulatory inspections conducted by the U.S. Environmental Protection Agency, Cal/OSHA, State of California Department of Health Services, and multiple county and municipal health departments and fire departments. He has decontaminated radioactive contaminated sites in Level C respiratory protection including hospital, laboratories, crematoriums, and outdoor environments. Mr. Silvers has presented hundreds of training courses on the subjects of 8-Hour HAZWOPER refresher, radiation safety, biological safety and blood borne pathogens, hazard communication, confined space entry, chemical hygiene, respiratory protection, laser safety, safe operation of forklifts, and general safety subjects such as company specific injury and Illness Prevention Programs. He has investigated workplace injuries and illnesses such as amputations and fatalities, maintained OSHA injury and illness records, performed construction safety oversight, performed facility wide environmental and safety audits, and performed workplace ergonomic evaluations. Mr. Silvers has written a great many clients site-specific written safety programs like Respiratory Protection, Confined Genoptix, Inc BioPharma Laboratory Technical Report/ Hazardous Materials Summary March 15, 2012 Page 35 Space Entry, Hazard Communication, Fire Prevention Plans, Hearing Conservation, Lockout/Tag out, Prevention of Workplace Violence, and Medical Surveillance. . Mr. Silvers, as the Alternate Radiation Safety Officer on Oasis State of California radioactive materials license performs hundreds of instrument calibrations each year, samples and analyzes unknown radio nuclides and completes sealed source leak testing. For Oasis clients, Mr. Silvers presents radiation safety training courses, completes radiation contamination surveys and closeout surveys as requested. Science Applications International Corporation (1991-1994) Mr. Silvers was a manager with the corporate Environmental Compliance & Health and Safety department at Science Applications International Corporation (ASAIC~) at the San Diego corporate headquarters. Mr. Silvers was the radiation safety officer (ARSO=) for Asics Broad scope Type B license. His corporate responsibilities included:· Health physics, 8-hour HAZWOPER training, writing, editing and reviewing of SAIC health and safety plans, industrial hygiene sampling, confined space sampling and permitting, laser safety, employee information and training, authoring company environmental compliance and safety procedures, site assessments of treatment, storage, disposal facilities (TSDF), authoring and reviewing site health and safety plans for hazardous waste operations and auditing of SAIC high risk locations and operations. Mr. Silvers was a member of the due diligence team performing reacquisition assessments and divestitures and provided health and safety legal s1:Jpport to Corporate Counsel. Mr. Silvers authored many original SAIC corporate health and safety procedures including Confined Space Entry, Lockout/Tag out, Medical Surveillance, Hearing Conservation,. Laser Safety, and Radiation Protection. Hughes Aircraft Company (1986'-1991-l Mr. Silvers was a Senior Environmental Health and Safety Engineer and Supervisor for Hughes Air_craft Company, in Carlsbad, California. His responsibilities at the semiconductor, laser, and cathode ray tube manufacturing plant included radiation safety officer for Hughes' radioactive materials license (kilocurie Co-60 irradiator), industrial hygiene sampling, confined space sampling and permitting, laser safety, environmental engineering, occupational injury and illness investigations, hazardous materials and hazardous waste management, TSCA compliance for PCBs, DOT shipment of hazardous materials, fire prevention, workers' compensation, accident statistics, coordinated and trained the emergency response team on responding to fires, chemical spills and toxic gas releases. He was also the chairman of biweekly safety conimittee and managed the department's annual fiscal budget. Mr. Silvers coordinated the annual physicals and medical surveillance of fifty employees annually. Mr. Silvers as a certified forklift instructor certified over sixty forklift operators. General Motors Assembly Plant, Van Nuys, CA (1984) Mr. Silvers was a safety engineer at the automotive assembly plant for the Cameron, Firebird, and Trans-Am, in Van Nuys, CA. Mr. Silvers performed confined space permitting and air sampling, respiratory protection training and fit testing, industrial hygiene sampling for organic solvents in the walk-in ,paint booth,. accident investigations, and noise sampling. Mr. Silvers reviewed material safety data sheets for accuracy and completeness, and compiled the plant's chemical inventory. PUBLICATIONS Depicter, A., Silvers, J.: Arsenic Levels in Hair of Workers in a Semiconductor Fabrication Facility, American Industrial Hygiene Association Journal, April 1995. PROFESSIONAL AFFILIATIONS: Mr. Silvers is a full member of the national American Industrial Hygiene Association and a current member and former director of membership for the s~m Diego section of the American Industrial Hygiene Association. Genoptix, Inc BioPharma Laboratory Technical. Report/ Hazardous Materials ~ummary Attachment 7 NCSA Certificate Number CFC0180.07 March 15, 2012 Page 36 Jeffrey A. Silvers, MPH, CIH, CSP: Certified California Fire Code Inspector NATIONAL CODE SERVICES ASSOCIATION Jeffrey A. Silvers, MPH, CIH, CSP Certified California Fire Code Inspector The Natiotu/ Code Scrvicc11hllocfatlon attul!I that ihe indh'id11al named on this ccrti.icate has satisfactoril.r demonstrated kaowkdgc of the California Fire Code by s11cccasfully completing the prcscdbcd written cxaminlltlon, based on the2(J07 edition. Witne ... ,,,, °"" hand Qnt(/ICICIC. No, C,COlB0,07 Iuue4: October 29, 20()9 For the National Code Ser!lices Association l,.,,... •. 1tJ. lJ.n .. -(} ~;;cip,Ch~, ' l. ____ .;.._;, __________________ __, _________________ .. ~r..· ~ «i~ ~ CITY OJ PLUMBIN'G, ELECTRICAL, MECHANICAL WORKSHE~T Development services Building Division 1635 Faraday Avenue 760-602-2719 www.carlsbadca.gov CARLSBAD 8-18 Prc;Jec:t Address: Permit No.: Information provided below Nfen foworll bmg ·done on the al:iove mentioned permit only. 1hls fp mu1t· 1M COl!Plttid and ret•raed.to the ·auilcllna Division before the permit.can.be iss·ued. . Bulld"1g Dept.Fax: (16Q)·do:i-asse . Number c,f new or~ ~, traps,.or floor drciins ........ ,.H111111M111MIH_111H1NIIIIMlllllfflNIII ,:z... New-~bllilclrlg sewer. line? ,..",.""",...,.,._, .. ~~•·• .... •···~ .. ~ ................. ~!"-''·"''~ ................ Yes_· ___ No ~ N...,,ber of~ roc>f drQlns? ........ ~ .................. ,',Y,tii••"*'" .......... !!-"' ....... -•• ~ ..................... ,H, ............ _£ Install/alter~ lfne? .. HNIIU1 .. n1• ........... ~ ........... HNIHIN!'IIHIIIHINHJHtHl'aHHI··· ... ··"'""'"""'' .. '""'"'"''''' ~ Number 0, nl\V·.wafer.·heaters? ...... H.,,-........ " ..... ; ••.••••••• ; ........................... -................................... ..¢_ Numbtir of i1e\U, relocated or repklced.gas outlets? .............................. -..................................... ~ Number .of ~:hose,blbs?-... -............... , .... H ........................... .;'! ............... m ..................................... ~ ·,, ~al Permftss ,: _-; :. ' New/expanded service: Number of new cimps: ..... · '_,,';:,,..· -~.,.-;~_,~~ __ ;: ................ __.. .... ,. . 'Mll'IQI' Rerrioder only: Yes__ No ){L_ -conunerclalllndustrlal: Tenant Improvement: Number of-alstflQI amps, irwo/wdin.thiutrofed:. <:·::S ~ • j ""'.. "' ... i' Numbet"of n•·amps_ inf/0/vedln tfiis;proi«f:. Newton,truclloni Ampsper-Panel: $ingle Phase ........ ~""'"'""· ... , ....................................... Number of new·amperes __ -,=f"'··5;:·:;o·d·.,,·"'1· ,,.·._-,---- rlhree Plidse' ... .-........ ., ................ M ..... , ... -.................. Number of neui·amperes __ ,;:J2=~ .. ~:,:· ~'":·.,-.,t.;..;·~ .. >_: ____ _ Three, PhQse 480·-... " ............. ~~"....._, .. ,_ .................... Number of new,amperes ____ ·;!.~!i~=-~,;-;-r .... ""~---------- N·umbtr of-new.furnaces; A/C;·or·heat:-pumps? ...................................................................... .-........ _,¢__ New or ~·d1.1Ct·wortai-. ................... " .. , ... ~ ......... ..-" .................................. Yes / No ___ _ Num~·of,neu, fireplqces?-, ... !' ......... _ .......... H.H .... ; ......... -•• , ........................ , ..................................... -$2(,. Number of new ~t fam? ........ ,.. ...... _ ... , ................ ~ ................... "' .................. ;~ ............................ ~ Relocate/Jmtall yent? _,..~ .. ·-··· .. -··· ............................................................................................... .:sz/.__ •-. ' Number of new ~t·hooclj?-........... 1 ............................ ,· ....... .;, ....................................................... ~ ""'-'mber Qf new:bl:,ifars ·or·cornpressors? ...... ....-_ ............................................. Number of flP __j;;t_ Page1 of 1 Rev.03/09